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    Bpifa2 BPI fold containing family A, member 2 [ Mus musculus (house mouse) ]

    Gene ID: 19194, updated on 5-Mar-2024

    Summary

    Official Symbol
    Bpifa2provided by MGI
    Official Full Name
    BPI fold containing family A, member 2provided by MGI
    Primary source
    MGI:MGI:97787
    See related
    Ensembl:ENSMUSG00000042459 AllianceGenome:MGI:97787
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Psp; Bpifa2e
    Summary
    Predicted to enable lipopolysaccharide binding activity. Predicted to act upstream of or within defense response to bacterium. Located in extracellular space. Is expressed in central nervous system; retina; and submandibular gland. Orthologous to human BPIFA2 (BPI fold containing family A member 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    Location:
    2 H1; 2 76.15 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (153850196..153857993)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (154008276..154016073)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene BPI fold containing family B, member 4 Neighboring gene BPI fold containing family A, member 6 Neighboring gene Friend virus susceptibility protein 1-like Neighboring gene STARR-seq mESC enhancer starr_06110 Neighboring gene BPI fold containing family A, member 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables lipopolysaccharide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables lipopolysaccharide binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    acts_upstream_of_or_within defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in secretory granule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in secretory granule ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    BPI fold-containing family A member 2
    Names
    BPI fold containing family A, member 2E
    parotid secretory protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008953.2NP_032979.1  BPI fold-containing family A member 2 precursor

      See identical proteins and their annotated locations for NP_032979.1

      Status: PROVISIONAL

      Source sequence(s)
      BC010288
      Consensus CDS
      CCDS16923.1
      UniProtKB/Swiss-Prot
      A2AIF8, P07743, Q9D734
      UniProtKB/TrEMBL
      B7ZCG3
      Related
      ENSMUSP00000046080.3, ENSMUST00000048103.9
      Conserved Domains (1) summary
      pfam01273
      Location:45214
      LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      153850196..153857993
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)