U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Magea5 MAGE family member A5 [ Mus musculus (house mouse) ]

    Gene ID: 17141, updated on 8-Feb-2024

    Summary

    Official Symbol
    Magea5provided by MGI
    Official Full Name
    MAGE family member A5provided by MGI
    Primary source
    MGI:MGI:1333838
    See related
    Ensembl:ENSMUSG00000079349 AllianceGenome:MGI:1333838
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mage-a5
    Summary
    Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in early conceptus and testis. Orthologous to human MAGEA10 (MAGE family member A10). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    X F3; X 72.38 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (153836057..153846147, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (155053061..155063151, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene MAGE family member A2 Neighboring gene predicted gene, 24268 Neighboring gene MAGE family member A1 Neighboring gene claudin 34B2 Neighboring gene predicted gene, 25429

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Clone Names

    • MGC130208

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables caspase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone deacetylase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in PML body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    melanoma antigen family A, 5
    Names
    melanoma antigen, family A, 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020018.1NP_064402.1  melanoma antigen family A, 5

      See identical proteins and their annotated locations for NP_064402.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ005529
      Consensus CDS
      CCDS30492.1
      UniProtKB/TrEMBL
      O89007, O89009
      Related
      ENSMUSP00000132644.2, ENSMUST00000169540.8
      Conserved Domains (2) summary
      pfam01454
      Location:134271
      MAGE; MAGE family
      pfam12440
      Location:4478
      MAGE_N; Melanoma associated antigen family N terminal

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      153836057..153846147 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006528725.1XP_006528788.1  melanoma antigen family A, 5 isoform X1

      See identical proteins and their annotated locations for XP_006528788.1

      UniProtKB/TrEMBL
      O89007, O89009
      Related
      ENSMUSP00000065852.4, ENSMUST00000069556.4
      Conserved Domains (2) summary
      pfam01454
      Location:134271
      MAGE; MAGE family
      pfam12440
      Location:4478
      MAGE_N; Melanoma associated antigen family N terminal
    2. XM_006528726.1XP_006528789.1  melanoma antigen family A, 5 isoform X1

      See identical proteins and their annotated locations for XP_006528789.1

      UniProtKB/TrEMBL
      O89007, O89009
      Conserved Domains (2) summary
      pfam01454
      Location:134271
      MAGE; MAGE family
      pfam12440
      Location:4478
      MAGE_N; Melanoma associated antigen family N terminal
    3. XM_006528727.2XP_006528790.1  melanoma antigen family A, 5 isoform X1

      See identical proteins and their annotated locations for XP_006528790.1

      UniProtKB/TrEMBL
      O89007, O89009
      Conserved Domains (2) summary
      pfam01454
      Location:134271
      MAGE; MAGE family
      pfam12440
      Location:4478
      MAGE_N; Melanoma associated antigen family N terminal

    RNA

    1. XR_001782740.1 RNA Sequence