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    Krt33b keratin 33B [ Mus musculus (house mouse) ]

    Gene ID: 16671, updated on 8-Feb-2024

    Summary

    Official Symbol
    Krt33bprovided by MGI
    Official Full Name
    keratin 33Bprovided by MGI
    Primary source
    MGI:MGI:1309991
    See related
    Ensembl:ENSMUSG00000057723 AllianceGenome:MGI:1309991
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ha3; Ha4; mHa3; Krt1-3
    Summary
    Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Is expressed in filiform papillae and integumental system. Orthologous to human KRT33A (keratin 33A) and KRT33B (keratin 33B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    Location:
    11 D; 11 63.37 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (99914460..99920694, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (100023634..100029868, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene keratin associated protein 17-1 Neighboring gene STARR-seq mESC enhancer starr_30710 Neighboring gene keratin 33A Neighboring gene keratin 34 Neighboring gene keratin 31

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in epithelial cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intermediate filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    keratin, type I cuticular Ha3-II
    Names
    K33B
    hair keratin, type I Ha3
    keratin complex 1, acidic, gene 3
    keratin complex 1, gene 3
    keratin, type I cuticular Ha3
    ortholog of keratin, hair, acidic, 3B KRTHA3B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013570.1NP_038598.1  keratin, type I cuticular Ha3-II

      See identical proteins and their annotated locations for NP_038598.1

      Status: VALIDATED

      Source sequence(s)
      AA169082, AA681979, AA762746, AI325228, AI466315
      Consensus CDS
      CCDS48928.1
      UniProtKB/Swiss-Prot
      A2A5X8, Q61897
      Related
      ENSMUSP00000073552.4, ENSMUST00000073890.4
      Conserved Domains (1) summary
      pfam00038
      Location:55366
      Filament; Intermediate filament protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      99914460..99920694 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)