Igkc immunoglobulin kappa constant [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Igkcprovided by MGI
Official Full Name: immunoglobulin kappa constantprovided by MGI
Primary source: MGI:MGI:96495
See related: Ensembl:ENSMUSG00000076609 IMGT/GENE-DB:IGKC; AllianceGenome:MGI:96495
Gene type: other
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Igk-C
Summary: Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Acts upstream of or within B cell differentiation. Predicted to be located in extracellular region and plasma membrane. Predicted to be part of immunoglobulin complex, circulating. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human IGKC (immunoglobulin kappa constant). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 6 C1; 6 32.04 cM

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	6	NC_000072.7 (70703419..70703738)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	6	NC_000072.6 (70726435..70726754)

Chromosome 6 - NC_000072.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (6) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH127636 (e-PCR)
- UniSTS:210946

Igk-C (e-PCR), detects polymorphism
- UniSTS:143505

Igk-C (e-PCR), detects polymorphism
- UniSTS:143506

Igk-C (e-PCR), detects polymorphism
- UniSTS:143507

AV061724 (e-PCR)
- UniSTS:179389

Other Names

If kappa light chain
immunoglobulin kappa chain, constant region
immunoglobulin variable region
kappa light chain C_region

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
acts_upstream_of_or_within B cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of IgG immunoglobulin complex	ISO Inferred from Sequence Orthology more info
located_in extracellular region	TAS Traceable Author Statement more info
located_in plasma membrane	TAS Traceable Author Statement more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.