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    Enah ENAH actin regulator [ Mus musculus (house mouse) ]

    Gene ID: 13800, updated on 21-Apr-2024

    Summary

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    Official Symbol
    Enahprovided by MGI
    Official Full Name
    ENAH actin regulatorprovided by MGI
    Primary source
    MGI:MGI:108360
    See related
    Ensembl:ENSMUSG00000022995 AllianceGenome:MGI:108360
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mena; WBP8; Ndpp1; NDPP-1
    Summary
    Enables SH3 domain binding activity and profilin binding activity. Involved in actin filament organization and actin polymerization-dependent cell motility. Acts upstream of or within actin polymerization or depolymerization; cellular response to leukemia inhibitory factor; and nervous system development. Located in several cellular components, including focal adhesion; lamellipodium; and stress fiber. Is expressed in several structures, including branchial arch; early embryo; gonad; limb bud; and nervous system. Orthologous to human ENAH (ENAH actin regulator). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E11.5 (RPKM 11.7), CNS E14 (RPKM 9.8) and 19 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    1 H5; 1 84.93 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (181723949..181848132, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (181896384..182027556, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3345 Neighboring gene STARR-seq mESC enhancer starr_03245 Neighboring gene predicted gene 5533 Neighboring gene STARR-positive B cell enhancer ABC_E10070 Neighboring gene predicted gene, 33669 Neighboring gene STARR-seq mESC enhancer starr_03248 Neighboring gene STARR-seq mESC enhancer starr_03253 Neighboring gene STARR-seq mESC enhancer starr_03255 Neighboring gene STARR-seq mESC enhancer starr_03256 Neighboring gene small nuclear ribonucleoprotein G pseudogene Neighboring gene STARR-seq mESC enhancer starr_03257 Neighboring gene STARR-seq mESC enhancer starr_03259 Neighboring gene STARR-seq mESC enhancer starr_03262 Neighboring gene predicted gene, 38648 Neighboring gene nuclear encoded tRNA serine 1 (anticodon GCT)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression. Oudin MJ, et al. Cancer Discov, 2016 May. PMID 26811325, Free PMC Article
    2. Cardiac overexpression of Mammalian enabled (Mena) exacerbates heart failure in mice. Belmonte SL, et al. Am J Physiol Heart Circ Physiol, 2013 Sep 15. PMID 23832697, Free PMC Article
    3. Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer. Roussos ET, et al. J Cell Sci, 2011 Jul 1. PMID 21670198, Free PMC Article
    4. Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM. Roussos ET, et al. Clin Exp Metastasis, 2011 Aug. PMID 21484349, Free PMC Article
    5. Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors. Roussos ET, et al. Breast Cancer Res, 2010. PMID 21108830, Free PMC Article

    See all (93) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA.
      Title: Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA.
    2. DJ-1 promotes cell migration by interacting with Mena, the mammalian homolog of Drosophila enabled.
      Title: DJ-1 promotes cell migration by interacting with Mena, the mammalian homolog of Drosophila enabled.
    3. these data provide the first description of endogenous Mena(INV) protein expression in mouse and human breast tumors.
      Title: Characterization of the expression of the pro-metastatic Mena(INV) isoform during breast tumor progression.
    4. Mena/VASP and alphaII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy.
      Title: Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy.
    5. These findings indicate that hearts with increased levels of Mena fare worse when subjected to cardiac injury and suggest that Mena contributes to HF pathophysiology.
      Title: Cardiac overexpression of Mammalian enabled (Mena) exacerbates heart failure in mice.
    6. Fibroblasts require Mena for multiple integrin alpha5beta1-dependent processes involving bidirectional interactions between the extracellular matrix and cytoplasmic focal adhesion proteins.
      Title: Mena binds α5 integrin directly and modulates α5β1 function.
    7. MenaINV increases coordinated streaming motility, and enhances transendothelial migration and intravasation of tumor cells.
      Title: Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer.
    8. Mena(INV)and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM.
      Title: Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM.
    9. deficiency of Mena decreases metastasis in transgenic mammary tumor by slowing progression and reducing tumor cell invasion and intravasation; mena deficiency during development causes defects in invasive processes involved in mammary gland development
      Title: Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors.
    10. Mammalian enabled (Mena) is a critical regulator of cardiac function.
      Title: Mammalian enabled (Mena) is a critical regulator of cardiac function.
    Submit: New GeneRIF Correction See all GeneRIFs (16)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SH3 domain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables SH3 domain binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables WW domain binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables profilin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables profilin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin cytoskeleton organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in actin filament organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in actin polymerization or depolymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within actin polymerization or depolymerization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in actin polymerization-dependent cell motility IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in actin polymerization-dependent cell motility IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within axon guidance IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cellular response to leukemia inhibitory factor IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within neural tube closure IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in anchoring junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in filopodium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in focal adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in lamellipodium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuron projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in stress fiber IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein enabled homolog
    Names
    NPC derived proline rich protein 1
    enabled homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083120.3 → NP_001076589.1  protein enabled homolog isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC122204, AC165229
      Consensus CDS
      CCDS48473.1
      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      UniProtKB/TrEMBL
      A0A0A6YW06
      Related
      ENSMUSP00000141344.2, ENSMUST00000195059.6
      Conserved Domains (2) summary
      cd01207
      Location:5 → 112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:748 → 781
      VASP_tetra; VASP tetramerization domain

    2. NM_001083121.3 → NP_001076590.1  protein enabled homolog isoform 4

      See identical proteins and their annotated locations for NP_001076590.1

      Status: VALIDATED

      Source sequence(s)
      AC122204, AC165229
      Consensus CDS
      CCDS78764.1
      UniProtKB/TrEMBL
      A0A0A6YXC8
      Related
      ENSMUSP00000141462.2, ENSMUST00000193703.6
      Conserved Domains (2) summary
      cd01207
      Location:5 → 112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:504 → 537
      VASP_tetra; VASP tetramerization domain

    3. NM_008680.4 → NP_032706.2  protein enabled homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC122204, AC165229
      Consensus CDS
      CCDS48474.1
      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      UniProtKB/TrEMBL
      E9QKQ9
      Related
      ENSMUSP00000106659.4, ENSMUST00000111030.6
      Conserved Domains (2) summary
      cd01207
      Location:5 → 112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:752 → 785
      VASP_tetra; VASP tetramerization domain

    4. NM_010135.4 → NP_034265.2  protein enabled homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC122204, AC165229
      Consensus CDS
      CCDS35811.1
      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      UniProtKB/TrEMBL
      E9QLZ9
      Related
      ENSMUSP00000077781.7, ENSMUST00000078719.13
      Conserved Domains (2) summary
      cd01207
      Location:5 → 112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:767 → 800
      VASP_tetra; VASP tetramerization domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      181723949..181848132 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159237.1 → XP_036015130.1  protein enabled homolog isoform X19

      UniProtKB/TrEMBL
      A0A0A6YXC8, E9QKR1
      Related
      ENSMUSP00000106653.5, ENSMUST00000111024.10
      Conserved Domains (3) summary
      cd01207
      Location:5 → 112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:525 → 559
      VASP_tetra; VASP tetramerisation domain
      cd22185
      Location:356 → 382
      WH2_hVASP-like; Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) of human Vasodilator-stimulated phosphoprotein and related proteins

    2. XM_006496652.4 → XP_006496715.1  protein enabled homolog isoform X20

      UniProtKB/TrEMBL
      A0A0A6YXC8
      Related
      ENSMUSP00000141936.2, ENSMUST00000193074.6
      Conserved Domains (2) summary
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:498 → 532
      VASP_tetra; VASP tetramerisation domain

    3. XM_006496651.5 → XP_006496714.1  protein enabled homolog isoform X18

      UniProtKB/TrEMBL
      A0A0A6YXC8
      Conserved Domains (2) summary
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:535 → 569
      VASP_tetra; VASP tetramerisation domain

    4. XM_006496650.4 → XP_006496713.1  protein enabled homolog isoform X15

      UniProtKB/TrEMBL
      A0A0A6YXC8
      Conserved Domains (2) summary
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:556 → 590
      VASP_tetra; VASP tetramerisation domain

    5. XM_006496646.5 → XP_006496709.1  protein enabled homolog isoform X8

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (3) summary
      PHA03247
      Location:333 → 553
      PHA03247; large tegument protein UL36; Provisional
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:779 → 813
      VASP_tetra; VASP tetramerisation domain

    6. XM_030247170.2 → XP_030103030.1  protein enabled homolog isoform X4

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (3) summary
      PHA03247
      Location:333 → 553
      PHA03247; large tegument protein UL36; Provisional
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:800 → 834
      VASP_tetra; VASP tetramerisation domain

    7. XM_030247143.2 → XP_030103003.1  protein enabled homolog isoform X2

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (3) summary
      PHA03247
      Location:352 → 572
      PHA03247; large tegument protein UL36; Provisional
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:819 → 853
      VASP_tetra; VASP tetramerisation domain

    8. XM_030247134.2 → XP_030102994.1  protein enabled homolog isoform X1

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (3) summary
      PHA03247
      Location:356 → 576
      PHA03247; large tegument protein UL36; Provisional
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:823 → 857
      VASP_tetra; VASP tetramerisation domain

    9. XM_030247158.2 → XP_030103018.1  protein enabled homolog isoform X3

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (3) summary
      PHA03247
      Location:337 → 557
      PHA03247; large tegument protein UL36; Provisional
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:804 → 838
      VASP_tetra; VASP tetramerisation domain

    10. XM_006496645.5 → XP_006496708.1  protein enabled homolog isoform X7

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (3) summary
      PHA03247
      Location:337 → 557
      PHA03247; large tegument protein UL36; Provisional
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:783 → 817
      VASP_tetra; VASP tetramerisation domain

    11. XM_036159112.1 → XP_036015005.1  protein enabled homolog isoform X13

      UniProtKB/TrEMBL
      A0A0A6YXC8
      Conserved Domains (3) summary
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:575 → 609
      VASP_tetra; VASP tetramerisation domain
      cd22185
      Location:406 → 432
      WH2_hVASP-like; Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) of human Vasodilator-stimulated phosphoprotein and related proteins

    12. XM_006496643.5 → XP_006496706.1  protein enabled homolog isoform X5

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (3) summary
      PHA03247
      Location:352 → 572
      PHA03247; large tegument protein UL36; Provisional
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:798 → 832
      VASP_tetra; VASP tetramerisation domain

    13. XM_036159177.1 → XP_036015070.1  protein enabled homolog isoform X16

      UniProtKB/TrEMBL
      A0A0A6YXC8
      Conserved Domains (3) summary
      cd01207
      Location:36 → 143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:554 → 588
      VASP_tetra; VASP tetramerisation domain
      cd22185
      Location:406 → 432
      WH2_hVASP-like; Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) of human Vasodilator-stimulated phosphoprotein and related proteins

    14. XM_006496648.4 → XP_006496711.1  protein enabled homolog isoform X11

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (2) summary
      PHA03247
      Location:231 → 451
      PHA03247; large tegument protein UL36; Provisional
      pfam08776
      Location:698 → 732
      VASP_tetra; VASP tetramerisation domain

    15. XM_006496649.5 → XP_006496712.1  protein enabled homolog isoform X12

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (2) summary
      PHA03247
      Location:227 → 447
      PHA03247; large tegument protein UL36; Provisional
      pfam08776
      Location:694 → 728
      VASP_tetra; VASP tetramerisation domain

    16. XM_036159132.1 → XP_036015025.1  protein enabled homolog isoform X14

      UniProtKB/TrEMBL
      A0A0A6YXC8
      Conserved Domains (3) summary
      cd01207
      Location:5 → 112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:568 → 602
      VASP_tetra; VASP tetramerisation domain
      cd22185
      Location:420 → 446
      WH2_hVASP-like; Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) of human Vasodilator-stimulated phosphoprotein and related proteins

    17. XM_006496647.5 → XP_006496710.1  protein enabled homolog isoform X10

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (3) summary
      PHA03247
      Location:302 → 522
      PHA03247; large tegument protein UL36; Provisional
      cd01207
      Location:5 → 112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:769 → 803
      VASP_tetra; VASP tetramerisation domain

    18. XM_036159054.1 → XP_036014947.1  protein enabled homolog isoform X9

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (4) summary
      PHA03247
      Location:306 → 526
      PHA03247; large tegument protein UL36; Provisional
      cd01207
      Location:5 → 112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:773 → 807
      VASP_tetra; VASP tetramerisation domain
      cd22185
      Location:604 → 630
      WH2_hVASP-like; Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) of human Vasodilator-stimulated phosphoprotein and related proteins

    19. XM_036159202.1 → XP_036015095.1  protein enabled homolog isoform X17

      UniProtKB/TrEMBL
      A0A0A6YXC8
      Conserved Domains (3) summary
      cd01207
      Location:5 → 112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:544 → 578
      VASP_tetra; VASP tetramerisation domain
      cd22185
      Location:375 → 401
      WH2_hVASP-like; Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) of human Vasodilator-stimulated phosphoprotein and related proteins

    20. XM_006496644.5 → XP_006496707.1  protein enabled homolog isoform X6

      UniProtKB/Swiss-Prot
      P70430, P70431, P70432, P70433, Q03173, Q5D053
      Conserved Domains (3) summary
      PHA03247
      Location:325 → 545
      PHA03247; large tegument protein UL36; Provisional
      cd01207
      Location:5 → 112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:792 → 826
      VASP_tetra; VASP tetramerisation domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03173.2 GenPept UniProtKB/Swiss-Prot:Q03173

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