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    Camk2b calcium/calmodulin-dependent protein kinase II, beta [ Mus musculus (house mouse) ]

    Gene ID: 12323, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Camk2bprovided by MGI
    Official Full Name
    calcium/calmodulin-dependent protein kinase II, betaprovided by MGI
    Primary source
    MGI:MGI:88257
    See related
    Ensembl:ENSMUSG00000057897 AllianceGenome:MGI:88257
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CaMKII
    Summary
    Enables calmodulin-dependent protein kinase activity. Involved in regulation of neuron migration. Acts upstream of or within several processes, including activation of meiosis involved in egg activation; modulation of chemical synaptic transmission; and protein phosphorylation. Located in cytosol; postsynaptic density; and spindle midzone. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeletal musculature. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 54. Orthologous to human CAMK2B (calcium/calmodulin dependent protein kinase II beta). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in frontal lobe adult (RPKM 115.3), cortex adult (RPKM 97.8) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    11 A1; 11 3.89 cM
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (5919642..6016401, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (5969629..6066357, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene glucokinase Neighboring gene STARR-positive B cell enhancer ABC_E6947 Neighboring gene predicted gene, 53665 Neighboring gene YKT6 v-SNARE homolog (S. cerevisiae) Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:5900191-5900374 Neighboring gene STARR-positive B cell enhancer ABC_E11764 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:5917894-5918003 Neighboring gene NudC domain containing 3 Neighboring gene STARR-seq mESC enhancer starr_28452 Neighboring gene STARR-seq mESC enhancer starr_28454 Neighboring gene ribosomal protein S15A, pseudogene 6 Neighboring gene STARR-positive B cell enhancer ABC_E10663 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:6100447-6100630 Neighboring gene NPC1 like intracellular cholesterol transporter 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Differential roles of CaMKII isoforms in phase separation with NMDA receptors and in synaptic plasticity. Cai Q, et al. Cell Rep, 2023 Mar 28. PMID 36827181
    2. Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP. Franz A, et al. Life Sci Alliance, 2023 Mar. PMID 36543542, Free PMC Article
    3. Adeno-associated virus-mediated expression of an inactive CaMKIIβ mutant enhances muscle mass and strength in mice. Eguchi T, et al. Biochem Biophys Res Commun, 2022 Jan 22. PMID 34922202
    4. The Wnt/Ca(2+) pathway is involved in interneuronal communication mediated by tunneling nanotubes. Vargas JY, et al. EMBO J, 2019 Dec 2. PMID 31625188, Free PMC Article
    5. Effects of HIV-1 Tat on oligodendrocyte viability are mediated by CaMKIIβ-GSK3β interactions. Zou S, et al. J Neurochem, 2019 Apr. PMID 30674062, Free PMC Article

    See all (123) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MFG-E8 facilitates heart repair through M1/M2 polarization after myocardial infarction by inhibiting CaMKII.
      Title: MFG-E8 facilitates heart repair through M1/M2 polarization after myocardial infarction by inhibiting CaMKII.
    2. CaMKII inhibition due to TRIC-B loss-of-function dysregulates SMAD signaling in osteogenesis imperfecta.
      Title: CaMKII inhibition due to TRIC-B loss-of-function dysregulates SMAD signaling in osteogenesis imperfecta.
    3. Differential roles of CaMKII isoforms in phase separation with NMDA receptors and in synaptic plasticity.
      Title: Differential roles of CaMKII isoforms in phase separation with NMDA receptors and in synaptic plasticity.
    4. CaMKII may regulate renal tubular epithelial cell apoptosis through YAP/NFAT2 in acute kidney injury mice.
      Title: CaMKII may regulate renal tubular epithelial cell apoptosis through YAP/NFAT2 in acute kidney injury mice.
    5. Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP.
      Title: Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP.
    6. GluN1 antibody causes behavioral deficits in prepulse inhibition and memory through CaMKIIbeta signaling.
      Title: GluN1 antibody causes behavioral deficits in prepulse inhibition and memory through CaMKIIβ signaling.
    7. A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIbeta Signaling in Limb Girdle Muscular Dystrophy.
      Title: A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy.
    8. Synaptic memory requires CaMKII.
      Title: Synaptic memory requires CaMKII.
    9. Adeno-associated virus-mediated expression of an inactive CaMKIIbeta mutant enhances muscle mass and strength in mice.
      Title: Adeno-associated virus-mediated expression of an inactive CaMKIIβ mutant enhances muscle mass and strength in mice.
    10. CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles.
      Title: CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles.
    Submit: New GeneRIF Correction See all GeneRIFs (35)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (10)  1 citation
    • Endonuclease-mediated (2) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC90738

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium-dependent protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables calmodulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calmodulin-dependent protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calmodulin-dependent protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables calmodulin-dependent protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phospholipase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables structural constituent of postsynaptic actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within G1/S transition of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within activation of meiosis involved in egg activation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of apoptotic signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within calcium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell projection morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within inhibitory G protein-coupled receptor phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within long-term synaptic potentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within neuromuscular process controlling balance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within peptidyl-serine phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of apoptotic signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of dendritic spine morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of neuron projection development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of synapse maturation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within protein autophosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of long-term neuronal synaptic plasticity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of neuron migration ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of synapse maturation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of synaptic transmission, cholinergic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cadmium ion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of calcium- and calmodulin-dependent protein kinase complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in perikaryon ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in sarcoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle midzone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    calcium/calmodulin-dependent protein kinase type II subunit beta
    Names
    CaMK II
    caM kinase II subunit beta
    caMK-II subunit beta
    NP_001167524.1
    NP_001167525.1
    NP_001404357.1
    NP_001404358.1
    NP_001404359.1
    NP_001404360.1
    NP_001404361.1
    NP_001404362.1
    NP_001404363.1
    NP_001404364.1
    NP_001404365.1
    NP_031621.3
    XP_006514527.1
    XP_006514528.1
    XP_006514530.1
    XP_006514532.1
    XP_006514533.1
    XP_017169726.1
    XP_017169727.1
    XP_017169730.1
    XP_030101361.1
    XP_030101363.1
    XP_030101364.1
    XP_030101365.1
    XP_030101366.1
    XP_030101367.1
    XP_036012149.1
    XP_036012150.1
    XP_036012151.1
    XP_036012152.1
    XP_036012153.1
    XP_036012154.1
    XP_036012155.1
    XP_036012156.1
    XP_036012158.1
    XP_036012160.1
    XP_036012161.1
    XP_036012162.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001174053.2 → NP_001167524.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 1

      See identical proteins and their annotated locations for NP_001167524.1

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469
      Consensus CDS
      CCDS48748.1
      UniProtKB/TrEMBL
      Q68EG2, Q8BL41
      Related
      ENSMUSP00000087925.4, ENSMUST00000090443.10
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:413 → 540
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    2. NM_001174054.2 → NP_001167525.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469
      Consensus CDS
      CCDS48749.1
      UniProtKB/TrEMBL
      Q5SVI2, Q8BL41
      Related
      ENSMUSP00000105437.3, ENSMUST00000109812.9
      Conserved Domains (2) summary
      cd14086
      Location:12 → 314
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:397 → 524
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    3. NM_001417428.1 → NP_001404357.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469

    4. NM_001417429.1 → NP_001404358.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469

    5. NM_001417430.1 → NP_001404359.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469

    6. NM_001417431.1 → NP_001404360.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469

    7. NM_001417432.1 → NP_001404361.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469

    8. NM_001417433.1 → NP_001404362.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469

    9. NM_001417434.1 → NP_001404363.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 10

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469

    10. NM_001417435.1 → NP_001404364.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 11

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469
      UniProtKB/TrEMBL
      Q5SVJ1
      Related
      ENSMUSP00000002817.6, ENSMUST00000002817.12

    11. NM_001417436.1 → NP_001404365.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 12

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469
      UniProtKB/TrEMBL
      Q5SVI0
      Related
      ENSMUSP00000099120.3, ENSMUST00000101586.3

    12. NM_007595.6 → NP_031621.3  calcium/calmodulin-dependent protein kinase type II subunit beta isoform 2

      See identical proteins and their annotated locations for NP_031621.3

      Status: VALIDATED

      Source sequence(s)
      AL611926, AL645469
      Consensus CDS
      CCDS24411.1
      UniProtKB/Swiss-Prot
      P28652, Q5SVH9
      UniProtKB/TrEMBL
      Q8BL41
      Related
      ENSMUSP00000105438.3, ENSMUST00000109813.9
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:410 → 537
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      5919642..6016401 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156268.1 → XP_036012161.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X29

      UniProtKB/TrEMBL
      Q3TY93
      Conserved Domains (2) summary
      pfam08332
      Location:281 → 408
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:1 → 174
      PKc_like; Protein Kinases, catalytic domain

    2. XM_030245507.2 → XP_030101367.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X34

      UniProtKB/TrEMBL
      Q3TY93
      Conserved Domains (2) summary
      pfam08332
      Location:210 → 337
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:38 → 142
      PKc_like; Protein Kinases, catalytic domain

    3. XM_030245506.2 → XP_030101366.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X33

      UniProtKB/TrEMBL
      Q3TY93
      Conserved Domains (2) summary
      pfam08332
      Location:225 → 352
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:38 → 142
      PKc_like; Protein Kinases, catalytic domain

    4. XM_036156269.1 → XP_036012162.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X31

      Conserved Domains (2) summary
      pfam08332
      Location:249 → 376
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:38 → 142
      PKc_like; Protein Kinases, catalytic domain

    5. XM_030245505.2 → XP_030101365.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X32

      UniProtKB/TrEMBL
      Q3TY93
      Conserved Domains (2) summary
      pfam08332
      Location:234 → 361
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:38 → 142
      PKc_like; Protein Kinases, catalytic domain

    6. XM_030245504.2 → XP_030101364.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X30

      Conserved Domains (2) summary
      pfam08332
      Location:250 → 377
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:38 → 142
      PKc_like; Protein Kinases, catalytic domain

    7. XM_036156258.1 → XP_036012151.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X11

      Conserved Domains (2) summary
      pfam08332
      Location:405 → 532
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:1 → 174
      PKc_like; Protein Kinases, catalytic domain

    8. XM_036156261.1 → XP_036012154.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X18

      Conserved Domains (2) summary
      pfam08332
      Location:381 → 508
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:1 → 174
      PKc_like; Protein Kinases, catalytic domain

    9. XM_030245501.2 → XP_030101361.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X10

      Conserved Domains (2) summary
      pfam08332
      Location:406 → 533
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:1 → 174
      PKc_like; Protein Kinases, catalytic domain

    10. XM_036156267.1 → XP_036012160.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X28

      UniProtKB/TrEMBL
      Q8BL41
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      cl09109
      Location:370 → 471
      NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...

    11. XM_006514470.5 → XP_006514533.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X8

      UniProtKB/TrEMBL
      Q8BL41
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:494 → 621
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    12. XM_036156265.1 → XP_036012158.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X25

      UniProtKB/TrEMBL
      Q8BL41
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      cl09109
      Location:385 → 486
      NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...

    13. XM_017314238.3 → XP_017169727.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X5

      UniProtKB/TrEMBL
      Q8BL41
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:509 → 636
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    14. XM_006514469.4 → XP_006514532.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X7

      UniProtKB/TrEMBL
      Q8BL41
      Related
      ENSMUSP00000091046.6, ENSMUST00000093355.12
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:495 → 622
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    15. XM_006514467.4 → XP_006514530.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X4

      UniProtKB/TrEMBL
      Q8BL41
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:510 → 637
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    16. XM_036156260.1 → XP_036012153.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X17

      UniProtKB/TrEMBL
      Q8BL41
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      cl09109
      Location:410 → 511
      NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...

    17. XM_006514465.4 → XP_006514528.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X2

      See identical proteins and their annotated locations for XP_006514528.1

      UniProtKB/TrEMBL
      Q5SVJ0, Q8BL41
      Related
      ENSMUSP00000019133.5, ENSMUST00000019133.11
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:534 → 661
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    18. XM_036156263.1 → XP_036012156.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X23

      UniProtKB/TrEMBL
      Q8BL41
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      cl09109
      Location:396 → 497
      NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...

    19. XM_017314237.3 → XP_017169726.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X3

      UniProtKB/TrEMBL
      Q8BL41
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:520 → 647
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    20. XM_036156259.1 → XP_036012152.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X16

      UniProtKB/TrEMBL
      Q8BL41
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      cl09109
      Location:411 → 512
      NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...

    21. XM_036156256.1 → XP_036012149.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X6

      UniProtKB/TrEMBL
      Q8BL41
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      cl09109
      Location:535 → 636
      NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...

    22. XM_006514464.4 → XP_006514527.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1

      UniProtKB/TrEMBL
      Q8BL41
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:535 → 662
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    23. XM_030245503.2 → XP_030101363.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X26

      Conserved Domains (2) summary
      pfam08332
      Location:349 → 476
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:38 → 142
      PKc_like; Protein Kinases, catalytic domain

    24. XM_036156262.1 → XP_036012155.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X20

      Conserved Domains (2) summary
      pfam08332
      Location:373 → 500
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:38 → 142
      PKc_like; Protein Kinases, catalytic domain

    25. XM_017314241.3 → XP_017169730.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X19

      Conserved Domains (2) summary
      pfam08332
      Location:374 → 501
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:38 → 142
      PKc_like; Protein Kinases, catalytic domain

    26. XM_036156257.1 → XP_036012150.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X10

      Conserved Domains (2) summary
      pfam08332
      Location:406 → 533
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:1 → 174
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P28652.2 GenPept UniProtKB/Swiss-Prot:P28652

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