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    Crybg1 crystallin beta-gamma domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 11630, updated on 21-Apr-2024

    Summary

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    Official Symbol
    Crybg1provided by MGI
    Official Full Name
    crystallin beta-gamma domain containing 1provided by MGI
    Primary source
    MGI:MGI:109544
    See related
    Ensembl:ENSMUSG00000019866 AllianceGenome:MGI:109544
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Aim1
    Summary
    Is expressed in several structures, including genitourinary system; heart; lung; skeletal musculature; and skin. Orthologous to human CRYBG1 (crystallin beta-gamma domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in large intestine adult (RPKM 7.7), bladder adult (RPKM 6.7) and 18 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    10 B2; 10 23.14 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (43826303..44024824, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (43950307..44148828, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_26525 Neighboring gene STARR-seq mESC enhancer starr_26526 Neighboring gene glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 Neighboring gene STARR-seq mESC enhancer starr_26527 Neighboring gene STARR-positive B cell enhancer ABC_E6838 Neighboring gene reticulon 4 interacting protein 1 Neighboring gene STARR-seq mESC enhancer starr_26529 Neighboring gene STARR-seq mESC enhancer starr_26530 Neighboring gene predicted gene, 40636 Neighboring gene STARR-seq mESC enhancer starr_26531 Neighboring gene STARR-seq mESC enhancer starr_26532 Neighboring gene STARR-seq mESC enhancer starr_26533 Neighboring gene preferentially expressed antigen in melanoma like 7 pseudogene Neighboring gene coiled-coil domain containing 137 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Cloning and tissue expression of the mouse ortholog of AIM1, a betagamma-crystallin superfamily member. Teichmann U, et al. Mamm Genome, 1998 Sep. PMID 9716656
    2. Physical and transcriptional map of the mouse Chromosome 10 proximal region syntenic to human 6q16-q21. Chalhoub N, et al. Mamm Genome, 2001 Dec. PMID 11707774
    3. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Tamplin OJ, et al. Dev Biol, 2011 Dec 15. PMID 22008794
    4. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    5. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3) 
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    beta/gamma crystallin domain-containing protein 1
    Names
    absent in melanoma 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368305.1 → NP_001355234.1  beta/gamma crystallin domain-containing protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC153534, AC153863, AC158637
      Consensus CDS
      CCDS88000.1
      UniProtKB/TrEMBL
      A0A0G2JG52
      Related
      ENSMUSP00000143429.2, ENSMUST00000200401.2
      Conserved Domains (5) summary
      PHA03247
      Location:445 → 1089
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:258 → 514
      PRK07003; DNA polymerase III subunit gamma/tau
      PRK07764
      Location:141 → 334
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00161
      Location:1933 → 2061
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00030
      Location:1563 → 1656
      Crystall; Beta/Gamma crystallin

    2. NM_001368306.1 → NP_001355235.1  beta/gamma crystallin domain-containing protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC153534, AC158637
      Conserved Domains (5) summary
      PHA03247
      Location:346 → 990
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:156 → 415
      PRK07003; DNA polymerase III subunit gamma/tau
      PRK07764
      Location:42 → 235
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00161
      Location:1834 → 1962
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00030
      Location:1464 → 1557
      Crystall; Beta/Gamma crystallin

    3. NM_172393.2 → NP_765981.2  beta/gamma crystallin domain-containing protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC153534, AC158637, AK041082
      Consensus CDS
      CCDS48553.1
      UniProtKB/TrEMBL
      E9PVP1
      Related
      ENSMUSP00000020017.9, ENSMUST00000020017.14
      Conserved Domains (3) summary
      PHA03247
      Location:22 → 715
      PHA03247; large tegument protein UL36; Provisional
      cd00161
      Location:1559 → 1687
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00030
      Location:1189 → 1282
      Crystall; Beta/Gamma crystallin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      43826303..44024824 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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