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    Vmn1r40 vomeronasal 1 receptor 40 [ Mus musculus (house mouse) ]

    Gene ID: 113855, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Vmn1r40provided by MGI
    Official Full Name
    vomeronasal 1 receptor 40provided by MGI
    Primary source
    MGI:MGI:2148518
    See related
    Ensembl:ENSMUSG00000096051 AllianceGenome:MGI:2148518
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    V1rb7
    Summary
    Predicted to enable signaling receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within sensory perception of chemical stimulus. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Orthologous to several human genes including VN1R17P (vomeronasal 1 receptor 17 pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    Location:
    6 D1; 6 40.02 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (89688243..89692117)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (89711261..89715135)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6453 Neighboring gene thioredoxin reductase 3 Neighboring gene vomeronasal 1 receptor, pseudogene 25 Neighboring gene vomeronasal 1 receptor 41 Neighboring gene vomeronasal 1 receptor, pseudogene 26

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Deficient pheromone responses in mice lacking a cluster of vomeronasal receptor genes. Del Punta K, et al. Nature, 2002 Sep 5. PMID 12214233
    2. Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse. Del Punta K, et al. Genome Res, 2000 Dec. PMID 11116090, Free PMC Article
    3. Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome. Amid C, et al. BMC Genomics, 2009 Dec 15. PMID 20003482, Free PMC Article
    4. Extreme variability among mammalian V1R gene families. Young JM, et al. Genome Res, 2010 Jan. PMID 19952141, Free PMC Article
    5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pheromone receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables signaling receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to pheromone IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sensory perception of chemical stimulus TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal type-1 receptor 40
    Names
    vomernasal 1 receptor Vmn1r40
    vomeronasal 1 receptor, B7
    vomeronasal type 1 receptor B7
    vomeronasal type-1 receptor A11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053228.1 → NP_444458.1  vomeronasal type-1 receptor 40

      See identical proteins and their annotated locations for NP_444458.1

      Status: PROVISIONAL

      Source sequence(s)
      AF291493
      Consensus CDS
      CCDS20346.1
      UniProtKB/Swiss-Prot
      Q9EQ46
      UniProtKB/TrEMBL
      F6MAD9, F6MAE6, F6MAE7, F6MAF3
      Related
      ENSMUSP00000074655.2, ENSMUST00000075158.2
      Conserved Domains (1) summary
      cd13949
      Location:12 → 305
      7tm_V1R_pheromone; vomeronasal organ pheromone receptor type-1 family, member of the seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      89688243..89692117
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505381.3 → XP_006505444.1  vomeronasal type-1 receptor 40 isoform X1

      See identical proteins and their annotated locations for XP_006505444.1

      UniProtKB/Swiss-Prot
      Q9EQ46
      UniProtKB/TrEMBL
      F6MAD9, F6MAE6, F6MAE7, F6MAF3
      Conserved Domains (1) summary
      cd13949
      Location:12 → 305
      7tm_V1R_pheromone; vomeronasal organ pheromone receptor type-1 family, member of the seven-transmembrane G protein-coupled receptor superfamily

    2. XM_006505382.3 → XP_006505445.1  vomeronasal type-1 receptor 40 isoform X1

      See identical proteins and their annotated locations for XP_006505445.1

      UniProtKB/Swiss-Prot
      Q9EQ46
      UniProtKB/TrEMBL
      F6MAD9, F6MAE6, F6MAE7, F6MAF3
      Related
      ENSMUSP00000154581.2, ENSMUST00000228642.2
      Conserved Domains (1) summary
      cd13949
      Location:12 → 305
      7tm_V1R_pheromone; vomeronasal organ pheromone receptor type-1 family, member of the seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9EQ46.1 GenPept UniProtKB/Swiss-Prot:Q9EQ46

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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