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    Zfp607b zinc finger protein 607B [ Mus musculus (house mouse) ]

    Gene ID: 112415, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp607bprovided by MGI
    Official Full Name
    zinc finger protein 607Bprovided by MGI
    Primary source
    MGI:MGI:2148237
    See related
    Ensembl:ENSMUSG00000057093 AllianceGenome:MGI:2148237
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C030039L03Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in bladder; male associated reproductive structure; testis; and urethra of male. Orthologous to human ZNF780A (zinc finger protein 780A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in CNS E18 (RPKM 3.0), testis adult (RPKM 2.2) and 10 other tissues See more
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    Genomic context

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    Location:
    7 A3; 7 15.96 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (27374086..27405909)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (27674661..27706484)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38973 Neighboring gene mitogen-activated protein kinase kinase kinase 10 Neighboring gene tetratricopeptide repeat domain 9B Neighboring gene STARR-seq mESC enhancer starr_18383 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:28474189-28474376 Neighboring gene STARR-seq mESC enhancer starr_18384 Neighboring gene PHD finger protein 5B, pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E10431 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:28516760-28516943 Neighboring gene zinc finger protein 60

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    2. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC112415

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001112731.1 → NP_001106202.1  uncharacterized protein LOC112415

      See identical proteins and their annotated locations for NP_001106202.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK141645, BC060708, CF727352
      Consensus CDS
      CCDS21029.1
      UniProtKB/TrEMBL
      G3X9H3
      Related
      ENSMUSP00000112494.2, ENSMUST00000120004.8
      Conserved Domains (4) summary
      smart00349
      Location:14 → 75
      KRAB; krueppel associated box
      COG5048
      Location:226 → 637
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:537 → 557
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl30559
      Location:174 → 239
      PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

    2. NM_198417.2 → NP_940809.2  uncharacterized protein LOC112415

      See identical proteins and their annotated locations for NP_940809.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate 5' UTR exon, as compared to variant 1.
      Source sequence(s)
      BC060708, BQ770435
      Consensus CDS
      CCDS21029.1
      UniProtKB/TrEMBL
      G3X9H3
      Conserved Domains (4) summary
      smart00349
      Location:14 → 75
      KRAB; krueppel associated box
      COG5048
      Location:226 → 637
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:537 → 557
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl30559
      Location:174 → 239
      PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      27374086..27405909
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030241994.2 → XP_030097854.1  uncharacterized protein LOC112415 isoform X1

      UniProtKB/TrEMBL
      G3X9H3
      Conserved Domains (4) summary
      smart00349
      Location:14 → 75
      KRAB; krueppel associated box
      COG5048
      Location:226 → 637
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:537 → 557
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl30559
      Location:174 → 239
      PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

    2. XM_030241995.1 → XP_030097855.1  uncharacterized protein LOC112415 isoform X1

      UniProtKB/TrEMBL
      G3X9H3
      Conserved Domains (4) summary
      smart00349
      Location:14 → 75
      KRAB; krueppel associated box
      COG5048
      Location:226 → 637
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:537 → 557
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl30559
      Location:174 → 239
      PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

    3. XM_030241993.1 → XP_030097853.1  uncharacterized protein LOC112415 isoform X1

      UniProtKB/TrEMBL
      G3X9H3
      Conserved Domains (4) summary
      smart00349
      Location:14 → 75
      KRAB; krueppel associated box
      COG5048
      Location:226 → 637
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:537 → 557
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl30559
      Location:174 → 239
      PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

    4. XM_036152574.1 → XP_036008467.1  uncharacterized protein LOC112415 isoform X1

      UniProtKB/TrEMBL
      G3X9H3
      Related
      ENSMUSP00000075755.7, ENSMUST00000076421.7
      Conserved Domains (4) summary
      smart00349
      Location:14 → 75
      KRAB; krueppel associated box
      COG5048
      Location:226 → 637
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:537 → 557
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl30559
      Location:174 → 239
      PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

    5. XM_030241992.2 → XP_030097852.1  uncharacterized protein LOC112415 isoform X1

      UniProtKB/TrEMBL
      G3X9H3
      Conserved Domains (4) summary
      smart00349
      Location:14 → 75
      KRAB; krueppel associated box
      COG5048
      Location:226 → 637
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:537 → 557
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl30559
      Location:174 → 239
      PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

    6. XM_036152572.1 → XP_036008465.1  uncharacterized protein LOC112415 isoform X1

      UniProtKB/TrEMBL
      G3X9H3
      Conserved Domains (4) summary
      smart00349
      Location:14 → 75
      KRAB; krueppel associated box
      COG5048
      Location:226 → 637
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:537 → 557
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl30559
      Location:174 → 239
      PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

    7. XM_036152573.1 → XP_036008466.1  uncharacterized protein LOC112415 isoform X1

      UniProtKB/TrEMBL
      G3X9H3
      Conserved Domains (4) summary
      smart00349
      Location:14 → 75
      KRAB; krueppel associated box
      COG5048
      Location:226 → 637
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:537 → 557
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl30559
      Location:174 → 239
      PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]
    Nucleotide Protein Strain
    Heading Accession and Version

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