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    Mrpl41 mitochondrial ribosomal protein L41 [ Mus musculus (house mouse) ]

    Gene ID: 107733, updated on 5-Mar-2024

    Summary

    Official Symbol
    Mrpl41provided by MGI
    Official Full Name
    mitochondrial ribosomal protein L41provided by MGI
    Primary source
    MGI:MGI:1333816
    See related
    Ensembl:ENSMUSG00000036850 AllianceGenome:MGI:1333816
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rpml27; MRP-L27
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to act upstream of or within apoptotic process. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL41 (mitochondrial ribosomal protein L41). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 10.1), CNS E14 (RPKM 10.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    Location:
    2 A3; 2 16.88 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (24862482..24865110, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (24972470..24975098, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene zinc finger, MYND domain containing 19 Neighboring gene STARR-positive B cell enhancer ABC_E5898 Neighboring gene diphthamine biosynethesis 7 Neighboring gene STARR-positive B cell enhancer ABC_E1001 Neighboring gene patatin-like phospholipase domain containing 7 Neighboring gene ribosomal protein L21 pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Transgenic (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrial translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial large ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein mL41
    Names
    39S ribosomal protein L41, mitochondrial
    L41mt
    MRP-L41

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001031808.2NP_001026978.2  large ribosomal subunit protein mL41 precursor

      See identical proteins and their annotated locations for NP_001026978.2

      Status: VALIDATED

      Source sequence(s)
      AK003340, AK011837, AK032370, AL732585
      Consensus CDS
      CCDS15744.1
      UniProtKB/Swiss-Prot
      Q8BJ44, Q9CQN7
      Related
      ENSMUSP00000043561.4, ENSMUST00000045604.4
      Conserved Domains (1) summary
      pfam09809
      Location:13125
      MRP-L27; Mitochondrial ribosomal protein L27

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      24862482..24865110 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)