U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Rpusd1 RNA pseudouridylate synthase domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 106707, updated on 11-Apr-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Rpusd1provided by MGI
    Official Full Name
    RNA pseudouridylate synthase domain containing 1provided by MGI
    Primary source
    MGI:MGI:1919186
    See related
    Ensembl:ENSMUSG00000041199 AllianceGenome:MGI:1919186
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rlucl; 2310051D06Rik
    Summary
    Predicted to enable pseudouridine synthase activity. Predicted to be involved in enzyme-directed rRNA pseudouridine synthesis. Orthologous to human RPUSD1 (RNA pseudouridine synthase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 37.8), ovary adult (RPKM 32.6) and 28 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Rpusd1 in Genome Data Viewer
    Location:
    17 A3.3; 17 12.83 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (25943758..25950438)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (25727703..25731464)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene NSA2 ribosome biogenesis homolog pseudogene Neighboring gene guanine nucleotide binding protein (G protein), gamma 13 Neighboring gene CTF18, chromosome transmission fidelity factor 18 Neighboring gene STARR-positive B cell enhancer ABC_E3190 Neighboring gene mesothelin-like Neighboring gene mesothelin

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA modification IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in enzyme-directed rRNA pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    RNA pseudouridylate synthase domain-containing protein 1
    Names
    ribosomal large subunit pseudouridine synthase C-like protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357176.1 → NP_001344105.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AI840239, AK009926, BY210331
      Consensus CDS
      CCDS89023.1
      UniProtKB/TrEMBL
      A0A494BAK7
      Related
      ENSMUST00000235645.2
      Conserved Domains (1) summary
      cd02869
      Location:6 → 86
      PseudoU_synth_RluA_like; Pseudouridine synthase, RluA family

    2. NM_028009.4 → NP_082285.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_082285.1

      Status: VALIDATED

      Source sequence(s)
      AI840239, AK049334, BY210331
      Consensus CDS
      CCDS28524.1
      UniProtKB/Swiss-Prot
      Q8VCZ8
      Related
      ENSMUSP00000043825.2, ENSMUST00000047273.3
      Conserved Domains (1) summary
      cd02869
      Location:18 → 215
      PseudoU_synth_RluA_like; Pseudouridine synthase, RluA family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      25943758..25950438
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160250.1 → XP_036016143.1  RNA pseudouridylate synthase domain-containing protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q8VCZ8
      Conserved Domains (1) summary
      cd02869
      Location:18 → 215
      PseudoU_synth_RluA_like; Pseudouridine synthase, RluA family

    2. XM_006523414.1 → XP_006523477.1  RNA pseudouridylate synthase domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006523477.1

      UniProtKB/Swiss-Prot
      Q8VCZ8
      Related
      ENSMUSP00000158547.2, ENSMUST00000237785.2
      Conserved Domains (1) summary
      cd02869
      Location:18 → 215
      PseudoU_synth_RluA_like; Pseudouridine synthase, RluA family

    3. XM_006523416.1 → XP_006523479.1  RNA pseudouridylate synthase domain-containing protein 1 isoform X2

      See identical proteins and their annotated locations for XP_006523479.1

      UniProtKB/TrEMBL
      A0A494BAK7
      Related
      ENSMUSP00000158085.2, ENSMUST00000237183.2
      Conserved Domains (1) summary
      cd02869
      Location:6 → 86
      PseudoU_synth_RluA_like; Pseudouridine synthase, RluA family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VCZ8.1 GenPept UniProtKB/Swiss-Prot:Q8VCZ8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous