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    Fam110c family with sequence similarity 110, member C [ Mus musculus (house mouse) ]

    Gene ID: 104943, updated on 5-Mar-2024

    Summary

    Official Symbol
    Fam110cprovided by MGI
    Official Full Name
    family with sequence similarity 110, member Cprovided by MGI
    Primary source
    MGI:MGI:1918813
    See related
    Ensembl:ENSMUSG00000036136 AllianceGenome:MGI:1918813
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9030611O19Rik
    Summary
    Predicted to enable alpha-tubulin binding activity. Predicted to be involved in positive regulation of cell migration; positive regulation of protein kinase B signaling; and regulation of cell projection assembly. Predicted to be located in cytoplasm; microtubule; and nucleus. Predicted to be active in cell cortex. Is expressed in adrenal gland and pancreas epithelium. Orthologous to human FAM110C (family with sequence similarity 110 member C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in colon adult (RPKM 8.1), bladder adult (RPKM 7.7) and 14 other tissues See more
    Orthologs
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    Genomic context

    Location:
    12 A2; 12 13.06 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (31123967..31129939)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (31073968..31079940)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene crumbs homolog 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_31847 Neighboring gene predicted gene, 25408 Neighboring gene predicted gene, 32443 Neighboring gene predicted gene, 40361 Neighboring gene SCAN domain containing 3 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables alpha-tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables alpha-tubulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cell cortex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027828.2NP_082104.2  protein FAM110C

      See identical proteins and their annotated locations for NP_082104.2

      Status: PROVISIONAL

      Source sequence(s)
      BC019466
      Consensus CDS
      CCDS25860.1
      UniProtKB/Swiss-Prot
      Q8VE94, Q9D322
      Related
      ENSMUSP00000041563.9, ENSMUST00000041133.10
      Conserved Domains (1) summary
      pfam14160
      Location:304409
      FAM110_C; Centrosome-associated C terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      31123967..31129939
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)