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    Pcnx3 pecanex homolog 3 [ Mus musculus (house mouse) ]

    Gene ID: 104401, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Pcnx3provided by MGI
    Official Full Name
    pecanex homolog 3provided by MGI
    Primary source
    MGI:MGI:1861733
    See related
    Ensembl:ENSMUSG00000054874 AllianceGenome:MGI:1861733
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pcnxl3; mKIAA4073
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human PCNX3 (pecanex 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in thymus adult (RPKM 60.8), adrenal adult (RPKM 58.7) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    19 A; 19 4.34 cM
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5714663..5739036, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5664635..5689003, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene v-rel reticuloendotheliosis viral oncogene homolog A (avian) Neighboring gene signal-induced proliferation associated gene 1 Neighboring gene microRNA 6987 Neighboring gene STARR-positive B cell enhancer ABC_E4259 Neighboring gene STARR-positive B cell enhancer ABC_E11012 Neighboring gene mitogen-activated protein kinase kinase kinase 11 Neighboring gene potassium channel, subfamily K, member 7 Neighboring gene EH domain binding protein 1-like 1 Neighboring gene family with sequence similarity 89, member B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genomic sequencing reveals the structure of the Kcnk6 and map3k11 genes and their close vicinity to the sipa1 gene on mouse chromosome 19. Saridaki A, et al. Cytogenet Cell Genet, 2000. PMID 10894943
    2. Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1. Park YG, et al. Nat Genet, 2005 Oct. PMID 16142231, Free PMC Article
    3. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
    4. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    5. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA4073

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    pecanex-like protein 3
    Names
    pecanex homolog protein 3
    pecanex-like 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144868.3 → NP_659117.2  pecanex-like protein 3

      See identical proteins and their annotated locations for NP_659117.2

      Status: VALIDATED

      Source sequence(s)
      BC096538, BE956025
      Consensus CDS
      CCDS29475.2
      UniProtKB/Swiss-Prot
      Q8VI59
      Related
      ENSMUSP00000109245.3, ENSMUST00000113615.9
      Conserved Domains (2) summary
      pfam05041
      Location:1570 → 1795
      Pecanex_C; Pecanex protein (C-terminus)
      cl21589
      Location:419 → 622
      Relaxase; Relaxase/Mobilization nuclease domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      5714663..5739036 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531613.5 → XP_006531676.1  pecanex-like protein 3 isoform X2

      Conserved Domains (3) summary
      PHA03247
      Location:194 → 654
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:1865 → 2034
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1582 → 1808
      Pecanex_C; Pecanex protein (C-terminus)

    2. XM_030250681.1 → XP_030106541.1  pecanex-like protein 3 isoform X7

      Conserved Domains (3) summary
      PHA03247
      Location:194 → 654
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:1852 → 2021
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1569 → 1795
      Pecanex_C; Pecanex protein (C-terminus)

    3. XM_006531612.4 → XP_006531675.1  pecanex-like protein 3 isoform X1

      Conserved Domains (3) summary
      PHA03247
      Location:194 → 655
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:1866 → 2035
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1583 → 1809
      Pecanex_C; Pecanex protein (C-terminus)

    4. XM_030250679.1 → XP_030106539.1  pecanex-like protein 3 isoform X4

      Conserved Domains (3) summary
      PHA03247
      Location:194 → 654
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:1859 → 2028
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1576 → 1802
      Pecanex_C; Pecanex protein (C-terminus)

    5. XM_011248596.4 → XP_011246898.1  pecanex-like protein 3 isoform X9

      Conserved Domains (3) summary
      PHA03247
      Location:194 → 655
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:1843 → 2012
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1560 → 1786
      Pecanex_C; Pecanex protein (C-terminus)

    6. XM_006531615.5 → XP_006531678.1  pecanex-like protein 3 isoform X8

      Conserved Domains (3) summary
      PHA03247
      Location:194 → 655
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:1850 → 2019
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1567 → 1793
      Pecanex_C; Pecanex protein (C-terminus)

    7. XM_011248595.4 → XP_011246897.1  pecanex-like protein 3 isoform X5

      Conserved Domains (3) summary
      PHA03247
      Location:194 → 655
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:1856 → 2025
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1573 → 1799
      Pecanex_C; Pecanex protein (C-terminus)

    8. XM_006531614.5 → XP_006531677.1  pecanex-like protein 3 isoform X3

      Conserved Domains (3) summary
      PHA03247
      Location:194 → 655
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:1860 → 2029
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1577 → 1803
      Pecanex_C; Pecanex protein (C-terminus)

    9. XM_030250682.2 → XP_030106542.1  pecanex-like protein 3 isoform X10

      Conserved Domains (3) summary
      PHA03247
      Location:194 → 654
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:1842 → 2011
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1559 → 1785
      Pecanex_C; Pecanex protein (C-terminus)

    10. XM_030250680.2 → XP_030106540.1  pecanex-like protein 3 isoform X6

      Conserved Domains (3) summary
      PHA03247
      Location:194 → 654
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:1855 → 2024
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05041
      Location:1572 → 1798
      Pecanex_C; Pecanex protein (C-terminus)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VI59.2 GenPept UniProtKB/Swiss-Prot:Q8VI59

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