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    Calhm5 calcium homeostasis modulator family member 5 [ Mus musculus (house mouse) ]

    Gene ID: 103511, updated on 11-Apr-2024

    Summary

    Official Symbol
    Calhm5provided by MGI
    Official Full Name
    calcium homeostasis modulator family member 5provided by MGI
    Primary source
    MGI:MGI:2143897
    See related
    Ensembl:ENSMUSG00000049872 AllianceGenome:MGI:2143897
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam26e
    Summary
    Predicted to enable cation channel activity. Predicted to act upstream of or within ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in medulla oblongata basal plate and thymus primordium. Orthologous to human CALHM5 (calcium homeostasis modulator family member 5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in bladder adult (RPKM 8.5), subcutaneous fat pad adult (RPKM 1.2) and 11 other tissues See more
    Orthologs
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    Genomic context

    Location:
    10 B1; 10 18.85 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (33967348..33972515, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (34091352..34096519, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RWD domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E9339 Neighboring gene trafficking protein particle complex 3 like Neighboring gene calcium homeostasis modulator family member 4 Neighboring gene STARR-seq mESC enhancer starr_26263 Neighboring gene STARR-positive B cell enhancer ABC_E11433 Neighboring gene calcium homeostasis modulator family member 6 Neighboring gene dermatan sulfate epimerase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables monoatomic cation channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    calcium homeostasis modulator protein 5
    Names
    family with sequence similarity 26, member E
    protein FAM26E

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178908.3NP_849239.2  calcium homeostasis modulator protein 5

      See identical proteins and their annotated locations for NP_849239.2

      Status: VALIDATED

      Source sequence(s)
      AK052861, AK085925
      Consensus CDS
      CCDS35879.1
      UniProtKB/Swiss-Prot
      Q8C3G8, Q8R100
      Related
      ENSMUSP00000064462.7, ENSMUST00000069125.8
      Conserved Domains (1) summary
      pfam14798
      Location:4251
      Ca_hom_mod; Calcium homeostasis modulator

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      33967348..33972515 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)