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    Acp7 acid phosphatase 7, tartrate resistant [ Mus musculus (house mouse) ]

    Gene ID: 101744, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Acp7provided by MGI
    Official Full Name
    acid phosphatase 7, tartrate resistantprovided by MGI
    Primary source
    MGI:MGI:2142121
    See related
    Ensembl:ENSMUSG00000037469 AllianceGenome:MGI:2142121
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Papl; C330005M16Rik
    Summary
    Predicted to enable acid phosphatase activity and metal ion binding activity. Predicted to be located in extracellular region. Orthologous to human ACP7 (acid phosphatase 7, tartrate resistant (putative)). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in stomach adult (RPKM 3.5), testis adult (RPKM 2.1) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    7 B1; 7 16.86 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28304055..28330755, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (28607322..28631332, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29342572-29342755 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29342797-29343021 Neighboring gene predicted gene, 38977 Neighboring gene microRNA 7049 Neighboring gene p21 (RAC1) activated kinase 4 Neighboring gene STARR-seq mESC enhancer starr_18428 Neighboring gene STARR-seq mESC enhancer starr_18429 Neighboring gene STARR-seq mESC enhancer starr_18430 Neighboring gene STARR-seq mESC enhancer starr_18432 Neighboring gene STARR-seq mESC enhancer starr_18434 Neighboring gene F-box protein 27 Neighboring gene F-box protein 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables acid phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    acid phosphatase type 7
    Names
    iron/zinc purple acid phospatase-like
    iron/zinc purple acid phosphatase-like protein
    purple acid phosphatase long form
    NP_780528.2
    XP_006539510.1
    XP_006539512.1
    XP_006539513.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175319.5 → NP_780528.2  acid phosphatase type 7 precursor

      Status: VALIDATED

      Source sequence(s)
      AC109162, AC136456
      Consensus CDS
      CCDS21050.2
      UniProtKB/Swiss-Prot
      Q8BX37
      Related
      ENSMUSP00000159320.2, ENSMUST00000239470.2
      Conserved Domains (2) summary
      cd00839
      Location:131 → 429
      MPP_PAPs; purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain
      pfam16656
      Location:32 → 124
      Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      28304055..28330755 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539449.5 → XP_006539512.1  acid phosphatase type 7 isoform X1

      See identical proteins and their annotated locations for XP_006539512.1

      UniProtKB/TrEMBL
      B2RRA7
      Conserved Domains (2) summary
      cd00839
      Location:189 → 487
      MPP_PAPs; purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain
      pfam16656
      Location:90 → 182
      Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain

    2. XM_006539447.5 → XP_006539510.1  acid phosphatase type 7 isoform X1

      See identical proteins and their annotated locations for XP_006539510.1

      UniProtKB/TrEMBL
      B2RRA7
      Related
      ENSMUSP00000045437.4, ENSMUST00000040112.5
      Conserved Domains (2) summary
      cd00839
      Location:189 → 487
      MPP_PAPs; purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain
      pfam16656
      Location:90 → 182
      Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain

    3. XM_006539450.3 → XP_006539513.1  acid phosphatase type 7 isoform X2

      See identical proteins and their annotated locations for XP_006539513.1

      UniProtKB/Swiss-Prot
      Q8BX37
      Related
      ENSMUSP00000147133.3, ENSMUST00000159560.3
      Conserved Domains (2) summary
      cd00839
      Location:131 → 429
      MPP_PAPs; purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain
      pfam16656
      Location:32 → 124
      Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BX37.2 GenPept UniProtKB/Swiss-Prot:Q8BX37

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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