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    Smim27 small integral membrane protein 27 [ Mus musculus (house mouse) ]

    Gene ID: 100504309, updated on 8-Mar-2024

    Summary

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    Official Symbol
    Smim27provided by MGI
    Official Full Name
    small integral membrane protein 27provided by MGI
    Primary source
    MGI:MGI:1913684
    See related
    Ensembl:ENSMUSG00000028407 AllianceGenome:MGI:1913684
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Toporsos; 2010003O02Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human SMIM27 (small integral membrane protein 27). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 44.5), ovary adult (RPKM 42.6) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    4 20.24 cM; 4 A5
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (40269579..40270228)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (40269579..40270228)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene aconitase 1 Neighboring gene STARR-seq mESC enhancer starr_09982 Neighboring gene RNA sensor RIG-I Neighboring gene STARR-seq mESC enhancer starr_09983 Neighboring gene STARR-positive B cell enhancer ABC_E6161 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:40216827-40216936 Neighboring gene topoisomerase I binding, arginine/serine-rich Neighboring gene STARR-seq mESC enhancer starr_09984 Neighboring gene NADH:ubiquinone oxidoreductase subunit B6 Neighboring gene RIKEN cDNA 4930509K18 gene Neighboring gene STARR-seq mESC enhancer starr_09985

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    small integral membrane protein 27
    Names
    TOPORS antisense RNA 1
    Topors opposite strand transcript
    topoisomerase I binding, arginine/serine-rich, opposite strand

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001349093.1 → NP_001336022.1  small integral membrane protein 27

      Status: VALIDATED

      Source sequence(s)
      AA190030, AL831793
      Consensus CDS
      CCDS89727.1
      UniProtKB/Swiss-Prot
      A0A140LHV9
      Related
      ENSMUSP00000146567.2, ENSMUST00000129758.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      40269579..40270228
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NR_045265.1: Suppressed sequence

      Description
      NR_045265.1: This RefSeq was removed because it is now thought that this gene does encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A140LHV9.1 GenPept UniProtKB/Swiss-Prot:A0A140LHV9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.