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    Ccdc13 coiled-coil domain containing 13 [ Mus musculus (house mouse) ]

    Gene ID: 100502861, updated on 12-Mar-2024

    Summary

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    Official Symbol
    Ccdc13provided by MGI
    Official Full Name
    coiled-coil domain containing 13provided by MGI
    Primary source
    MGI:MGI:1920144
    See related
    Ensembl:ENSMUSG00000079235 AllianceGenome:MGI:1920144
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm188; 2900041A11Rik
    Summary
    Predicted to be involved in cellular response to DNA damage stimulus; cytoplasmic microtubule organization; and non-motile cilium assembly. Predicted to act upstream of or within cell projection organization. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be active in centriolar satellite. Is expressed in submandibular gland primordium. Orthologous to human CCDC13 (coiled-coil domain containing 13). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 19.1) and frontal lobe adult (RPKM 1.0) See more
    Orthologs
    human all
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    Genomic context

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    Location:
    9 F4; 9 72.63 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (121626690..121668581, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (121797624..121839515, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene kelch-like 40 Neighboring gene hedgehog acyltransferase-like Neighboring gene predicted gene, 51698 Neighboring gene HIG1 domain family, member 1A Neighboring gene STARR-positive B cell enhancer ABC_E3869 Neighboring gene predicted gene, 47112 Neighboring gene predicted gene, 47113

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Stauber M, et al. Dev Biol, 2017 Mar 15. PMID 27914912
    2. Gene expression in the developing mouse retina by EST sequencing and microarray analysis. Mu X, et al. Nucleic Acids Res, 2001 Dec 15. PMID 11812828, Free PMC Article
    3. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
    4. Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Li J, et al. Nat Neurosci, 2017 Aug. PMID 28671696, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC182513

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within cell projection organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cytoplasmic microtubule organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cytoplasmic microtubule organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in non-motile cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within non-motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in centriolar satellite IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028384.1 → NP_082660.1  coiled-coil domain-containing protein 13

      See identical proteins and their annotated locations for NP_082660.1

      Status: PROVISIONAL

      Source sequence(s)
      AC165080, AW911821, BB762565, BB857029, BC147354, BG800529, BM949737, BY082969, BY296983
      Consensus CDS
      CCDS57717.1
      UniProtKB/Swiss-Prot
      D3YV10
      Related
      ENSMUSP00000114787.3, ENSMUST00000135986.9
      Conserved Domains (2) summary
      COG1196
      Location:76 → 444
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:306 → 599
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      121626690..121668581 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036154496.1 → XP_036010389.1  coiled-coil domain-containing protein 13 isoform X2

      Conserved Domains (1) summary
      COG1196
      Location:76 → 444
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. XM_006511904.4 → XP_006511967.1  coiled-coil domain-containing protein 13 isoform X1

      See identical proteins and their annotated locations for XP_006511967.1

      UniProtKB/Swiss-Prot
      D3YV10
      Conserved Domains (2) summary
      COG1196
      Location:76 → 444
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:306 → 599
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    3. XM_011242925.3 → XP_011241227.1  coiled-coil domain-containing protein 13 isoform X1

      See identical proteins and their annotated locations for XP_011241227.1

      UniProtKB/Swiss-Prot
      D3YV10
      Conserved Domains (2) summary
      COG1196
      Location:76 → 444
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:306 → 599
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    4. XM_036154498.1 → XP_036010391.1  coiled-coil domain-containing protein 13 isoform X5

      Conserved Domains (1) summary
      TIGR02168
      Location:1 → 293
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    5. XM_036154497.1 → XP_036010390.1  coiled-coil domain-containing protein 13 isoform X5

      Conserved Domains (1) summary
      TIGR02168
      Location:1 → 293
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    6. XM_006511906.1 → XP_006511969.1  coiled-coil domain-containing protein 13 isoform X3

      Conserved Domains (1) summary
      COG1196
      Location:76 → 444
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    7. XM_011242926.2 → XP_011241228.1  coiled-coil domain-containing protein 13 isoform X4

      Conserved Domains (1) summary
      COG1196
      Location:76 → 444
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    8. XM_030243930.1 → XP_030099790.1  coiled-coil domain-containing protein 13 isoform X4

      Conserved Domains (1) summary
      COG1196
      Location:76 → 444
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RNA

    1. XR_004935290.1 RNA Sequence

    2. XR_004935288.1 RNA Sequence

    3. XR_004935289.1 RNA Sequence

    4. XR_379845.3 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001033784.3: Suppressed sequence

      Description
      NM_001033784.3: This RefSeq was permanently suppressed because the CDS was partial.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    D3YV10.1 GenPept UniProtKB/Swiss-Prot:D3YV10

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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