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    Zfp729b zinc finger protein 729b [ Mus musculus (house mouse) ]

    Gene ID: 100416706, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp729bprovided by MGI
    Official Full Name
    zinc finger protein 729bprovided by MGI
    Primary source
    MGI:MGI:2145180
    See related
    Ensembl:ENSMUSG00000058093 AllianceGenome:MGI:2145180
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and negative regulation of transposon integration. Predicted to be located in nucleus. Orthologous to human ZNF91 (zinc finger protein 91). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in bladder adult (RPKM 1.6), CNS E18 (RPKM 1.4) and 23 other tissues See more
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    Genomic context

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    See Zfp729b in Genome Data Viewer
    Location:
    13 B3; 13 34.59 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (67737558..67757767, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (67589439..67609707, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 748 Neighboring gene RIKEN cDNA 9430065F17 gene Neighboring gene STARR-positive B cell enhancer ABC_E9881 Neighboring gene STARR-positive B cell enhancer ABC_E4077 Neighboring gene STARR-seq mESC enhancer starr_34905 Neighboring gene zinc finger protein 729a Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:67738709-67738896 Neighboring gene predicted gene, 46439

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Potential readthrough

    Included genes: Zfp87, Zfp58

    Homology

    Clone Names

    • MGC54886

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein
    Names
    Novel C2H2 type zinc finger protein (AA987161)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163246.3 → NP_001156718.1  zinc finger protein isoform 1

      See identical proteins and their annotated locations for NP_001156718.1

      Status: VALIDATED

      Source sequence(s)
      CT573016
      Consensus CDS
      CCDS56892.1
      UniProtKB/TrEMBL
      Q80VN4
      Related
      ENSMUSP00000012873.9, ENSMUST00000012873.16
      Conserved Domains (5) summary
      smart00349
      Location:5 → 63
      KRAB; krueppel associated box
      COG5048
      Location:466 → 879
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:778 → 798
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:5 → 44
      KRAB; KRAB box
      pfam13465
      Location:482 → 505
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001401859.1 → NP_001388788.1  zinc finger protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      CT573016

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      67737558..67757767 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_019411.1: Suppressed sequence

      Description
      NG_019411.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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