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    Trac T cell receptor alpha constant [ Mus musculus (house mouse) ]

    Gene ID: 100101484, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Tracprovided by MGI
    Official Full Name
    T cell receptor alpha constantprovided by MGI
    Primary source
    MGI:MGI:4439838
    See related
    IMGT/GENE-DB:TRAC; AllianceGenome:MGI:4439838
    Gene type
    other
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tcra; Tcra-C; Gm16914
    Summary
    Predicted to be involved in response to bacterium. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    14 27.7 cM; 14 C2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (54457978..54461655)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (54220521..54224198)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene T cell receptor alpha chain Neighboring gene STARR-positive B cell enhancer ABC_E7311 Neighboring gene CapStarr-seq enhancers MGSCv37_chr14:54846812-54847013 and MGSCv37_chr14:54847102-54847395 Neighboring gene STARR-positive B cell enhancer ABC_E5435 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:54852981-54853251 Neighboring gene STARR-positive B cell enhancer ABC_E1168 Neighboring gene T cell receptor alpha joining 2 Neighboring gene T cell receptor alpha joining 1 Neighboring gene abhydrolase domain containing 4 Neighboring gene defender against cell death 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and expression of transcripts of the T-cell antigen receptor alpha-chain gene in a functional, antigen-specific suppressor-T-cell hybridoma. Imai K, et al. Proc Natl Acad Sci U S A, 1986 Nov. PMID 2946043, Free PMC Article
    2. Biological transfer of the CBA Tcra locus into C57BL/6 mice. Rubin B, et al. Immunogenetics, 1990. PMID 1969386
    3. Cloning of an unidentified T-cell receptor alpha chain gene from a vesicular stomatitis virus-specific helper T-cell clone. Ghelardi E, et al. Immunol Lett, 1996 Oct. PMID 8946215
    4. Striking sequence similarity over almost 100 kilobases of human and mouse T-cell receptor DNA. Koop BF, et al. Nat Genet, 1994 May. PMID 8075639
    5. A new mouse T-cell receptor alpha chain variable region family. Sutherland RM, et al. Immunogenetics, 1991. PMID 1684175

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Other Names

    • T-cell receptor alpha, constant region

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables signaling receptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in response to bacterium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of alpha-beta T cell receptor complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_007044.1 

      Range
      1793055..1796732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      54457978..54461655
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P01849.2 GenPept UniProtKB/Swiss-Prot:P01849

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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    Research Materials