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EIF2B5 - eukaryotic translation initiation factor 2B subunit epsilon

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]

Genes similar to EIF2B5

NCBI Orthologs

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Species Gene Architecture aa