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ARF4 auxin response factor 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836166, updated on 7-Sep-2023

Summary

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Gene symbol
ARF4
Gene description
auxin response factor 4
Primary source
Araport:AT5G60450
Locus tag
AT5G60450
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
auxin response factor 4; MUF9.7; MUF9_7
Summary
Encodes a member of the ARF family of transcription factors which mediate auxin responses. ARF4 appears to have redundant function with ETT(ARF3) in specifying abaxial cell identity.
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Genomic context

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Location:
chromosome: 5
Exon count:
13
Sequence:
Chromosome: 5; NC_003076.8 (24308255..24312784, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene antiporter/ drug transporter Neighboring gene AGAMOUS-like 62 Neighboring gene Preprotein translocase Sec, Sec61-beta subunit protein Neighboring gene C2H2 and C2HC zinc fingers superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Trans-acting siRNA-mediated repression of ETTIN and ARF4 regulates heteroblasty in Arabidopsis. Hunter C, et al. Development, 2006 Aug. PMID 16818444, Free PMC Article
  2. ARF4 regulates shoot regeneration through coordination with ARF5 and IAA12. Zhang MM, et al. Plant Cell Rep, 2021 Feb. PMID 33180161
  3. ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis. Liu Z, et al. Plant Cell Physiol, 2018 Jan 1. PMID 29145642
  4. Auxin response factors mediate Arabidopsis organ asymmetry via modulation of KANADI activity. Pekker I, et al. Plant Cell, 2005 Nov. PMID 16199616, Free PMC Article
  5. A gain-of-function mutation in IAA8 alters Arabidopsis floral organ development by change of jasmonic acid level. Wang J, et al. Plant Mol Biol, 2013 May. PMID 23483289

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ARF4 regulates shoot regeneration through coordination with ARF5 and IAA12.
    Title: ARF4 regulates shoot regeneration through coordination with ARF5 and IAA12.
  2. Results indicate that auxin response factors AtARF2-AtARF4 and AtARF5 play significant roles in regulating both female and male gametophyte development.
    Title: ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
  3. regulation establishes the threshold at which leaves respond to a temporal signal, rather than being a component of this signal.
    Title: Trans-acting siRNA-mediated repression of ETTIN and ARF4 regulates heteroblasty in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Miscellaneous features

  • Loc: c24312539-24312456 AT5G60450.uORF1
NM_125438.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within abaxial cell fate specification IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vegetative phase change IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
auxin response factor 4
NP_200853.1
  • auxin response factor 4 (ARF4); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: vegetative phase change, regulation of transcription, DNA-dependent, abaxial cell fate specification; LOCATED IN: nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Aux/IAA-ARF-dimerisation (InterPro:IPR011525), Transcriptional factor B3 (InterPro:IPR003340), AUX/IAA protein (InterPro:IPR003311), Auxin response factor (InterPro:IPR010525); BEST Arabidopsis thaliana protein match is: Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-related (TAIR:AT2G33860.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    24308255..24312784 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001345418.1 → NP_001331788.1  auxin response factor 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BF20, A0A7G2FJJ2

  2. NM_125438.4 → NP_200853.1  auxin response factor 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_200853.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9ZTX9
    UniProtKB/TrEMBL
    A0A178ULQ0, A0A654GCU3
    Conserved Domains (3) summary
    pfam02309
    Location:636 → 735
    AUX_IAA; AUX/IAA family
    pfam02362
    Location:177 → 278
    B3; B3 DNA binding domain
    pfam06507
    Location:302 → 383
    Auxin_resp; Auxin response factor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZTX9.1

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