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AK3 aspartate kinase 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821287, updated on 15-Oct-2023

Summary

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Gene symbol
AK3
Gene description
aspartate kinase 3
Primary source
Araport:AT3G02020
Locus tag
AT3G02020
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
aspartate kinase 3; F1C9.20; F1C9_20
Summary
encodes a monofunctional aspartate kinase
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Genomic context

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Location:
chromosome: 3
Exon count:
13
Sequence:
Chromosome: 3; NC_003074.8 (337712..343912, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene ACT domain repeat 6 Neighboring gene Thioredoxin superfamily protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene transferase Neighboring gene senescence-related gene 3 Neighboring gene K+ uptake transporter 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a monofunctional aspartate kinase gene of Arabidopsis thaliana with spatially and temporally regulated expression. Yoshioka Y, et al. Genes Genet Syst, 2001 Jun. PMID 11569502
  2. Cloning and expression of an Arabidopsis thaliana cDNA encoding a monofunctional aspartate kinase homologous to the lysine-sensitive enzyme of Escherichia coli. Tang G, et al. Plant Mol Biol, 1997 May. PMID 9207844
  3. Allosteric monofunctional aspartate kinases from Arabidopsis. Curien G, et al. FEBS J, 2007 Jan. PMID 17140415
  4. Analysis of Loss-of-Function Mutants in Aspartate Kinase and Homoserine Dehydrogenase Genes Points to Complexity in the Regulation of Aspartate-Derived Amino Acid Contents. Clark TJ, et al. Plant Physiol, 2015 Aug. PMID 26063505, Free PMC Article
  5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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NM_111068.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables aspartate kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables aspartate kinase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within aspartate family amino acid biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
involved_in lysine biosynthetic process via diaminopimelate IEA
Inferred from Electronic Annotation
more info
  
involved_in threonine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
aspartate kinase 3
NP_186851.1
  • aspartate kinase 3 (AK3); CONTAINS InterPro DOMAIN/s: Aspartate kinase, conserved site (InterPro:IPR018042), Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), Amino acid-binding ACT (InterPro:IPR002912), Aspartate kinase domain (InterPro:IPR001341); BEST Arabidopsis thaliana protein match is: Aspartate kinase family protein (TAIR:AT5G14060.2); Has 11044 Blast hits to 11020 proteins in 2545 species: Archae - 256; Bacteria - 7570; Metazoa - 4; Fungi - 149; Plants - 183; Viruses - 0; Other Eukaryotes - 2882 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    337712..343912 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111068.4 → NP_186851.1  aspartate kinase 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_186851.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9S702
    UniProtKB/TrEMBL
    A0A5S9X8E7, A0A654FDS8
    Conserved Domains (1) summary
    PLN02551
    Location:32 → 552
    PLN02551; aspartokinase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9S702.1

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