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PEX13 peroxin 13 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819945, updated on 15-Oct-2023

Summary

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Gene symbol
PEX13
Gene description
peroxin 13
Primary source
Araport:AT3G07560
Locus tag
AT3G07560
See related
TAIR:AT3G07560
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ABERRANT PEROXISOME MORPHOLOGY 2; APM2; peroxin 13
Summary
Encodes peroxin 13 (PEX13) involved in protein transport into peroxisomes, for example, peroxisomal import of nitric oxide synthase.
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Genomic context

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See PEX13 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Sequence:
Chromosome: 3; NC_003074.8 (2411321..2413587, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene autophagocytosis-associated family protein Neighboring gene integrator complex subunit Neighboring gene Actin-binding FH2 (formin homology 2) family protein Neighboring gene RNI-like superfamily protein Neighboring gene histone H2A deubiquitinase (DUF3755) Neighboring gene fanconi anemia group D2 protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A viable Arabidopsis pex13 missense allele confers severe peroxisomal defects and decreases PEX5 association with peroxisomes. Woodward AW, et al. Plant Mol Biol, 2014 Sep. PMID 25008153, Free PMC Article
  2. Reducing PEX13 expression ameliorates physiological defects of late-acting peroxin mutants. Ratzel SE, et al. Traffic, 2011 Jan. PMID 20969679, Free PMC Article
  3. The peroxin loss-of-function mutation abstinence by mutual consent disrupts male-female gametophyte recognition. Boisson-Dernier A, et al. Curr Biol, 2008 Jan 8. PMID 18160292, Free PMC Article
  4. Peroxisomes are required for in vivo nitric oxide accumulation in the cytosol following salinity stress of Arabidopsis plants. Corpas FJ, et al. Plant Physiol, 2009 Dec. PMID 19783645, Free PMC Article
  5. Arabidopsis DAYU/ABERRANT PEROXISOME MORPHOLOGY9 is a key regulator of peroxisome biogenesis and plays critical roles during pollen maturation and germination in planta. Li XR, et al. Plant Cell, 2014 Feb. PMID 24510720, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PEX13 has a role in plant peroxisome receptor docking and matrix protein import.
    Title: A viable Arabidopsis pex13 missense allele confers severe peroxisomal defects and decreases PEX5 association with peroxisomes.
  2. pex13-1 allele had deleterious effects when combined with pex5-1 and pex14-2, which are defective in early-acting peroxins, as shown by reduced matrix protein import and enhanced physiological defects
    Title: Reducing PEX13 expression ameliorates physiological defects of late-acting peroxin mutants.
  3. AMC is strongly and transiently expressed in both male and female gametophytes during fertilization and functions in gametophytes as a peroxin essential for protein import into peroxisomes.
    Title: The peroxin loss-of-function mutation abstinence by mutual consent disrupts male-female gametophyte recognition.
  4. APM2/PEX13 and APM4/PEX12 have roles in both PTS1- and PTS2-dependent protein transport on the peroxisomal membrane. [APM2] [PEX13]
    Title: The Arabidopsis pex12 and pex13 mutants are defective in both PTS1- and PTS2-dependent protein transport to peroxisomes.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_111634.6

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within fatty acid beta-oxidation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein import into peroxisome matrix IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within protein import into peroxisome matrix IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein import into peroxisome matrix, docking IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in intracellular anatomical structure IDA
Inferred from Direct Assay
more info
 PubMed 
located_in peroxisomal membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
peroxin 13
NP_187412.1
  • peroxin 13 (PEX13); Has 58927 Blast hits to 16541 proteins in 1193 species: Archae - 47; Bacteria - 25769; Metazoa - 16443; Fungi - 3404; Plants - 6224; Viruses - 432; Other Eukaryotes - 6608 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    2411321..2413587 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111634.6 → NP_187412.1  peroxin 13 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187412.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C0Z2M3, Q9SRR0
    UniProtKB/TrEMBL
    A0A178VBD0, A0A5S9XA12, A0A7G2EKS1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SRR0.1

Gene LinkOut

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