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Mrgprh MAS-related GPR, member H [ Mus musculus (house mouse) ]

Gene ID: 80978, updated on 11-Apr-2024

Summary

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Official Symbol
Mrgprhprovided by MGI
Official Full Name
MAS-related GPR, member Hprovided by MGI
Primary source
MGI:MGI:1934134
See related
Ensembl:ENSMUSG00000059408 AllianceGenome:MGI:1934134
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mgrb; MrgH; Gpr90
Summary
Predicted to enable angiotensin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
17 A1; 17 8.7 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (13094921..13096729)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (12876034..12877842)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene antisense Igf2r RNA Neighboring gene ribosomal protein L41 pseudogene Neighboring gene MAS1 oncogene Neighboring gene predicted gene, 53988 Neighboring gene poly(A)-specific ribonuclease (PARN)-like domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E2471 Neighboring gene mitochondrial ribosomal protein L18 Neighboring gene t-complex protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors. Wittenberger T, et al. J Mol Biol, 2001 Mar 30. PMID 11273702
  2. Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway. Han SK, et al. Proc Natl Acad Sci U S A, 2002 Nov 12. PMID 12397184, Free PMC Article
  3. A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Dong X, et al. Cell, 2001 Sep 7. PMID 11551509
  4. Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Zylka MJ, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12909716, Free PMC Article
  5. Comparative genomic analysis of eutherian Mas-related G protein-coupled receptor genes. Premzl M. Gene, 2014 Apr 25. PMID 24583173

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables angiotensin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
mas-related G-protein coupled receptor member H
Names
G protein-coupled receptor 90
G-protein coupled receptor GPR90
Mas-related G protein-coupled receptor b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030726.1 → NP_109651.1  mas-related G-protein coupled receptor member H

    See identical proteins and their annotated locations for NP_109651.1

    Status: PROVISIONAL

    Source sequence(s)
    AF295365
    Consensus CDS
    CCDS28395.1
    UniProtKB/Swiss-Prot
    Q149S2, Q99MT8
    UniProtKB/TrEMBL
    W8W3M0
    Related
    ENSMUSP00000074768.3, ENSMUST00000075296.4
    Conserved Domains (2) summary
    pfam00001
    Location:51 → 279
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:42 → 215
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    13094921..13096729
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99MT8.1 GenPept UniProtKB/Swiss-Prot:Q99MT8

Gene LinkOut

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