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scyl1 SCY1-like, kinase-like 1 [ Danio rerio (zebrafish) ]

Gene ID: 793792, updated on 27-Mar-2024

Summary

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Official Symbol
scyl1provided by ZNC
Official Full Name
SCY1-like, kinase-like 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8915
See related
Ensembl:ENSDARG00000079854 AllianceGenome:ZFIN:ZDB-GENE-030131-8915
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fk36e11; wu:fk36e11; si:ch211-276i12.7
Summary
Predicted to enable ATP binding activity and protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 21. Orthologous to human SCYL1 (SCY1 like pseudokinase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
18
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (45575035..45595743, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (46587748..46608446, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene retinoic acid receptor responder 3 Neighboring gene retinoic acid receptor responder 3-like Neighboring gene si:ch211-276i12.9 Neighboring gene zgc:194285 Neighboring gene si:ch211-276i12.4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Expression and function of lncRNA MALAT-1 in the embryonic development of zebrafish. Wu M, et al. Gene, 2019 Jan 5. PMID 30248354
  2. Identification of Potential Long Noncoding RNA Biomarker of Mercury Compounds in Zebrafish Embryos. Cao M, et al. Chem Res Toxicol, 2019 May 20. PMID 30912647
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
N-terminal kinase-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    45575035..45595743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001332472.6 → XP_001332508.1  N-terminal kinase-like protein

    UniProtKB/TrEMBL
    A0A8M1Q6V7, E7F3D6
    Related
    ENSDARP00000068527.3, ENSDART00000074038.5
    Conserved Domains (3) summary
    pfam02985
    Location:504 → 534
    HEAT; HEAT repeat
    sd00044
    Location:348 → 369
    HEAT; HEAT repeat [structural motif]
    cl21453
    Location:28 → 293
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

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