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Fam219b family with sequence similarity 219, member B [ Mus musculus (house mouse) ]

Gene ID: 78323, updated on 5-Mar-2024

Summary

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Official Symbol
Fam219bprovided by MGI
Official Full Name
family with sequence similarity 219, member Bprovided by MGI
Primary source
MGI:MGI:1925573
See related
Ensembl:ENSMUSG00000032305 AllianceGenome:MGI:1925573
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310046O06Rik
Summary
Orthologous to human FAM219B (family with sequence similarity 219 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 4.8), adrenal adult (RPKM 4.7) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
9 B; 9 31.05 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (57443648..57450471)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (57536685..57543188)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_24239 Neighboring gene ribonuclease P/MRP 25 subunit Neighboring gene STARR-positive B cell enhancer ABC_E11408 Neighboring gene cytochrome c oxidase subunit 5A Neighboring gene mannose phosphate isomerase Neighboring gene STARR-positive B cell enhancer ABC_E3834 Neighboring gene STARR-positive B cell enhancer ABC_E3835 Neighboring gene secretory carrier membrane protein 2 Neighboring gene unc-51-like kinase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein FAM219B
Names
uncharacterized protein C15orf17 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166364.1 → NP_001159836.1  protein FAM219B isoform 1

    See identical proteins and their annotated locations for NP_001159836.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK028365, AV370547, BC112403
    Consensus CDS
    CCDS52807.1
    UniProtKB/Swiss-Prot
    Q14DQ1, Q8BSZ6
    Related
    ENSMUSP00000109838.3, ENSMUST00000114200.10
    Conserved Domains (1) summary
    pfam15260
    Location:72 → 197
    FAM219A; Protein family FAM219A

  2. NM_175273.4 → NP_780482.1  protein FAM219B isoform 2

    See identical proteins and their annotated locations for NP_780482.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks a frame-shifting exon in the 3' coding region, compared to variant 1. This difference results in a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK028365, AV370547, BC112403
    Consensus CDS
    CCDS52808.1
    UniProtKB/Swiss-Prot
    Q14DQ1
    Related
    ENSMUSP00000091353.5, ENSMUST00000093833.6
    Conserved Domains (1) summary
    pfam15260
    Location:72 → 128
    FAM219A; Protein family FAM219A

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    57443648..57450471
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511558.5 → XP_006511621.3  protein FAM219B isoform X1

    Conserved Domains (1) summary
    pfam15260
    Location:120 → 224
    FAM219A; Protein family FAM219A

  2. XM_006511559.5 → XP_006511622.3  protein FAM219B isoform X2

    Conserved Domains (1) summary
    pfam15260
    Location:120 → 175
    FAM219A; Protein family FAM219A
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q14DQ1.1 GenPept UniProtKB/Swiss-Prot:Q14DQ1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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