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Map7d2 MAP7 domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 78283, updated on 11-Apr-2024

Summary

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Official Symbol
Map7d2provided by MGI
Official Full Name
MAP7 domain containing 2provided by MGI
Primary source
MGI:MGI:1917474
See related
Ensembl:ENSMUSG00000041020 AllianceGenome:MGI:1917474
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mtap7d2; 1600028E09Rik; 2900002G04Rik; 5330432J06Rik; C030036K04Rik
Summary
Predicted to be involved in microtubule cytoskeleton organization. Predicted to be active in microtubule cytoskeleton. Is expressed in nervous system. Orthologous to human MAP7D2 (MAP7 domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 18.4), frontal lobe adult (RPKM 11.9) and 6 other tissues See more
Orthologs
human all
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Genomic context

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Location:
X F4; X 73.45 cM
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (158197488..158281954)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (159414492..159498958)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 1A, X-linked Neighboring gene predicted gene 15187 Neighboring gene STARR-seq mESC enhancer starr_48172 Neighboring gene STARR-seq mESC enhancer starr_48173 Neighboring gene predicted gene, 39546 Neighboring gene STARR-seq mESC enhancer starr_48174 Neighboring gene STARR-positive B cell enhancer mm9_chrX:155970286-155970586 Neighboring gene Bclaf1 and Thrap3 family member 3 Neighboring gene hepatitis B virus x interacting protein pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Phenotypic annotation of the mouse X chromosome. Cox BJ, et al. Genome Res, 2010 Aug. PMID 20548051, Free PMC Article
  2. Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant. Quinlan MA, et al. Front Mol Neurosci, 2020. PMID 32581705, Free PMC Article
  3. Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies. Murtaza N, et al. Cell Rep, 2022 Nov 22. PMID 36417873
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
MAP7 domain-containing protein 2
Names
novel E-MAP-115 family protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081124.2 → NP_001074593.1  MAP7 domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_001074593.1

    Status: VALIDATED

    Source sequence(s)
    AK013466, AK030316, AL672284, BE952779, CK620800
    Consensus CDS
    CCDS41193.1
    UniProtKB/Swiss-Prot
    A2AG50, A2AG54, Q8BLE6, Q8BMQ4, Q9D2A4
    Related
    ENSMUSP00000108090.3, ENSMUST00000112471.9
    Conserved Domains (2) summary
    pfam05672
    Location:433 → 608
    MAP7; MAP7 (E-MAP-115) family
    pfam11208
    Location:76 → 141
    DUF2992; Protein of unknown function (DUF2992)

  2. NM_001313751.1 → NP_001300680.1  MAP7 domain-containing protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK030316, AK162227, BE952779, CK620800
    UniProtKB/Swiss-Prot
    A2AG50
    UniProtKB/TrEMBL
    Q3TS73
    Conserved Domains (2) summary
    pfam05672
    Location:400 → 575
    MAP7; MAP7 (E-MAP-115) family
    pfam11208
    Location:76 → 141
    DUF2992; Protein of unknown function (DUF2992)

  3. NM_001313752.1 → NP_001300681.1  MAP7 domain-containing protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AK019929
    Consensus CDS
    CCDS85823.1
    UniProtKB/Swiss-Prot
    A2AG50
    Related
    ENSMUSP00000108089.2, ENSMUST00000112470.3
    Conserved Domains (1) summary
    pfam05672
    Location:249 → 276
    MAP7; MAP7 (E-MAP-115) family

  4. NM_001313753.1 → NP_001300682.1  MAP7 domain-containing protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AK019929, AK030316, BE952779
    Consensus CDS
    CCDS85824.1
    UniProtKB/Swiss-Prot
    A2AG50
    Related
    ENSMUSP00000046693.6, ENSMUST00000043151.12
    Conserved Domains (1) summary
    pfam05672
    Location:247 → 424
    MAP7; MAP7 (E-MAP-115) family

  5. NM_001359310.1 → NP_001346239.1  MAP7 domain-containing protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL672284, BE952779
    Conserved Domains (2) summary
    pfam05672
    Location:433 → 589
    MAP7; MAP7 (E-MAP-115) family
    cl25549
    Location:75 → 168
    ARGLU; Arginine and glutamate-rich 1

  6. NM_001359311.1 → NP_001346240.1  MAP7 domain-containing protein 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL672284, BE952779
    Conserved Domains (2) summary
    pfam05672
    Location:396 → 571
    MAP7; MAP7 (E-MAP-115) family
    cl25742
    Location:75 → 164
    ERM; Ezrin/radixin/moesin family

  7. NM_001359313.1 → NP_001346242.1  MAP7 domain-containing protein 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL672284, BE952779
    Conserved Domains (2) summary
    pfam05672
    Location:400 → 556
    MAP7; MAP7 (E-MAP-115) family
    cl25742
    Location:75 → 164
    ERM; Ezrin/radixin/moesin family

  8. NM_001359314.1 → NP_001346243.1  MAP7 domain-containing protein 2 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AL672284, BE952779
    Conserved Domains (2) summary
    pfam05672
    Location:396 → 552
    MAP7; MAP7 (E-MAP-115) family
    cl25549
    Location:75 → 168
    ARGLU; Arginine and glutamate-rich 1

  9. NM_001359315.1 → NP_001346244.1  MAP7 domain-containing protein 2 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AL672284, BE952779
    Conserved Domains (2) summary
    pfam05672
    Location:363 → 538
    MAP7; MAP7 (E-MAP-115) family
    pfam05914
    Location:70 → 141
    RIB43A; RIB43A

  10. NM_001359317.1 → NP_001346246.1  MAP7 domain-containing protein 2 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AL672284, BE952779
    Conserved Domains (2) summary
    pfam05672
    Location:363 → 519
    MAP7; MAP7 (E-MAP-115) family
    pfam05914
    Location:70 → 141
    RIB43A; RIB43A

  11. NM_001359320.1 → NP_001346249.1  MAP7 domain-containing protein 2 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AL672284, BE952779
    Conserved Domains (1) summary
    pfam05672
    Location:280 → 457
    MAP7; MAP7 (E-MAP-115) family

  12. NM_001359321.1 → NP_001346250.1  MAP7 domain-containing protein 2 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AL672284, BE952779
    Conserved Domains (1) summary
    pfam05672
    Location:282 → 438
    MAP7; MAP7 (E-MAP-115) family

  13. NM_001359322.1 → NP_001346251.1  MAP7 domain-containing protein 2 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AL672284, BE952779
    Conserved Domains (1) summary
    pfam05672
    Location:212 → 382
    MAP7; MAP7 (E-MAP-115) family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    158197488..158281954
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017318641.2 → XP_017174130.1  MAP7 domain-containing protein 2 isoform X2

    Conserved Domains (2) summary
    pfam05672
    Location:361 → 533
    MAP7; MAP7 (E-MAP-115) family
    pfam17380
    Location:75 → 168
    DUF5401; Family of unknown function (DUF5401)

  2. XM_011247881.4 → XP_011246183.1  MAP7 domain-containing protein 2 isoform X1

    Conserved Domains (2) summary
    pfam05672
    Location:431 → 603
    MAP7; MAP7 (E-MAP-115) family
    pfam17380
    Location:75 → 168
    DUF5401; Family of unknown function (DUF5401)

  3. XM_036162119.1 → XP_036018012.1  MAP7 domain-containing protein 2 isoform X4

    Conserved Domains (1) summary
    pfam05672
    Location:247 → 419
    MAP7; MAP7 (E-MAP-115) family

  4. XM_030251520.1 → XP_030107380.1  MAP7 domain-containing protein 2 isoform X5

    Conserved Domains (1) summary
    pfam05672
    Location:280 → 457
    MAP7; MAP7 (E-MAP-115) family

  5. XM_030251519.2 → XP_030107379.1  MAP7 domain-containing protein 2 isoform X3

    Conserved Domains (1) summary
    pfam05672
    Location:247 → 424
    MAP7; MAP7 (E-MAP-115) family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2AG50.1 GenPept UniProtKB/Swiss-Prot:A2AG50

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