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Lcn9 lipocalin 9 [ Mus musculus (house mouse) ]

Gene ID: 77704, updated on 5-Mar-2024

Summary

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Official Symbol
Lcn9provided by MGI
Official Full Name
lipocalin 9provided by MGI
Primary source
MGI:MGI:1924954
See related
Ensembl:ENSMUSG00000023210 AllianceGenome:MGI:1924954
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9230102I19Rik
Summary
Predicted to enable small molecule binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human LCN9 (lipocalin 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward genital fat pad adult (RPKM 720.6) See more
Orthologs
human all
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Genomic context

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Location:
2 A3; 2 18.15 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25713100..25715558)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25823088..25825546)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 13539 Neighboring gene glycosyltransferase 6 domain containing 1 Neighboring gene predicted gene, 35689 Neighboring gene spermatogenesis and oogenesis specific basic helix-loop-helix 1 Neighboring gene STARR-seq mESC enhancer starr_03968 Neighboring gene potassium channel, subfamily T, member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Transcriptome profiling of the initial segment and proximal caput of mouse epididymis. Wang X, et al. Front Endocrinol (Lausanne), 2023. PMID 37324270, Free PMC Article
  2. Deficiency for Lcn8 causes epididymal sperm maturation defects in mice. Wen Z, et al. Biochem Biophys Res Commun, 2021 Apr 9. PMID 33631677
  3. A novel mouse line with epididymal initial segment-specific expression of Cre recombinase driven by the endogenous Lcn9 promoter. Gong QQ, et al. PLoS One, 2021. PMID 34310634, Free PMC Article
  4. Molecular evolution of epididymal lipocalin genes localized on mouse chromosome 2. Suzuki K, et al. Gene, 2004 Sep 15. PMID 15363845
  5. Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom". Charkoftaki G, et al. Hum Genomics, 2019 Feb 19. PMID 30782214, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A novel mouse line with epididymal initial segment-specific expression of Cre recombinase driven by the endogenous Lcn9 promoter.
    Title: A novel mouse line with epididymal initial segment-specific expression of Cre recombinase driven by the endogenous Lcn9 promoter.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (3)  1 citation

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables small molecule binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
epididymal-specific lipocalin-9
Names
MUP-like lipocalin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029959.2 → NP_084235.1  epididymal-specific lipocalin-9 precursor

    See identical proteins and their annotated locations for NP_084235.1

    Status: VALIDATED

    Source sequence(s)
    AK020305
    Consensus CDS
    CCDS15792.1
    UniProtKB/Swiss-Prot
    Q80ZC4, Q9D267
    Related
    ENSMUSP00000023978.3, ENSMUST00000023978.3
    Conserved Domains (1) summary
    pfam00061
    Location:34 → 174
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    25713100..25715558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319341.2 → XP_017174830.1  epididymal-specific lipocalin-9 isoform X4

    Conserved Domains (1) summary
    cl10502
    Location:2 → 142
    lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family

  2. XM_017319340.2 → XP_017174829.1  epididymal-specific lipocalin-9 isoform X3

    Conserved Domains (1) summary
    cd19429
    Location:21 → 173
    lipocalin_9; lipocalin 9

  3. XM_017319338.1 → XP_017174827.1  epididymal-specific lipocalin-9 isoform X1

    Conserved Domains (1) summary
    cd19429
    Location:69 → 210
    lipocalin_9; lipocalin 9

  4. XM_017319339.1 → XP_017174828.1  epididymal-specific lipocalin-9 isoform X2

    Conserved Domains (1) summary
    cd19429
    Location:69 → 213
    lipocalin_9; lipocalin 9
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D267.1 GenPept UniProtKB/Swiss-Prot:Q9D267

Gene LinkOut

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