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Lrriq3 leucine-rich repeats and IQ motif containing 3 [ Mus musculus (house mouse) ]

Gene ID: 74435, updated on 5-Mar-2024

Summary

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Official Symbol
Lrriq3provided by MGI
Official Full Name
leucine-rich repeats and IQ motif containing 3provided by MGI
Primary source
MGI:MGI:1921685
See related
Ensembl:ENSMUSG00000028182 AllianceGenome:MGI:1921685
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lrrc44; 4930438B07Rik; 4930511J15Rik; 4933403H06Rik
Summary
Orthologous to human LRRIQ3 (leucine rich repeats and IQ motif containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 6.7) and genital fat pad adult (RPKM 0.2) See more
Orthologs
human all
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Genomic context

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Location:
3 H4; 3 79.54 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (154799032..154899915)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (155093395..155194278)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene TNNI3 interacting kinase Neighboring gene leucine rich repeat containing 4 pseudogene Neighboring gene STARR-seq mESC enhancer starr_09350 Neighboring gene STARR-seq mESC enhancer starr_09351 Neighboring gene STARR-seq mESC enhancer starr_09352 Neighboring gene STARR-seq mESC enhancer starr_09353 Neighboring gene STARR-positive B cell enhancer ABC_E7951 Neighboring gene fucose-1-phosphate guanylyltransferase Neighboring gene STARR-seq mESC enhancer starr_09354 Neighboring gene STARR-seq mESC enhancer starr_09355 Neighboring gene STARR-seq mESC enhancer starr_09356 Neighboring gene sperm motility kinase 3A pseudogene Neighboring gene STARR-seq mESC enhancer starr_09358 Neighboring gene sterol carrier protein 2, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC132959

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
leucine-rich repeat and IQ domain-containing protein 3
Names
leucine rich repeat containing 44
leucine-rich repeat-containing protein 44

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028938.2 → NP_083214.2  leucine-rich repeat and IQ domain-containing protein 3

    See identical proteins and their annotated locations for NP_083214.2

    Status: VALIDATED

    Source sequence(s)
    AK132656, BB019345, BY080708
    Consensus CDS
    CCDS38682.1
    UniProtKB/Swiss-Prot
    Q14DL3, Q9D4C3, Q9D562, Q9D5I0
    Related
    ENSMUSP00000029833.8, ENSMUST00000029833.13
    Conserved Domains (3) summary
    sd00031
    Location:52 → 73
    LRR_1; leucine-rich repeat [structural motif]
    pfam12252
    Location:459 → 630
    SidE; Dot/Icm substrate protein
    pfam13855
    Location:51 → 109
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    154799032..154899915
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006502189.3 → XP_006502252.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006502252.1

    UniProtKB/Swiss-Prot
    Q14DL3, Q9D4C3, Q9D562, Q9D5I0
    Conserved Domains (3) summary
    sd00031
    Location:52 → 73
    LRR_1; leucine-rich repeat [structural motif]
    pfam12252
    Location:459 → 630
    SidE; Dot/Icm substrate protein
    pfam13855
    Location:51 → 109
    LRR_8; Leucine rich repeat

  2. XM_006502190.5 → XP_006502253.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X2

    See identical proteins and their annotated locations for XP_006502253.1

    UniProtKB/Swiss-Prot
    Q14DL3
    Related
    ENSMUSP00000141372.2, ENSMUST00000192383.6
    Conserved Domains (2) summary
    sd00031
    Location:52 → 73
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:51 → 109
    LRR_8; Leucine rich repeat

  3. XM_017319774.3 → XP_017175263.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X3

    Related
    ENSMUSP00000142127.2, ENSMUST00000194376.2
    Conserved Domains (2) summary
    sd00031
    Location:52 → 73
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:51 → 109
    LRR_8; Leucine rich repeat
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q14DL3.1 GenPept UniProtKB/Swiss-Prot:Q14DL3

Gene LinkOut

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