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Phospho2 phosphatase, orphan 2 [ Mus musculus (house mouse) ]

Gene ID: 73373, updated on 11-Apr-2024

Summary

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Official Symbol
Phospho2provided by MGI
Official Full Name
phosphatase, orphan 2provided by MGI
Primary source
MGI:MGI:1920623
See related
Ensembl:ENSMUSG00000027088 AllianceGenome:MGI:1920623
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Phos2; 1700048E23Rik
Summary
Predicted to enable phosphatase activity. Orthologous to human PHOSPHO2 (phosphatase, orphan 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 58.1), adrenal adult (RPKM 8.9) and 25 other tissues See more
Orthologs
human all
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Genomic context

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Location:
2 C2; 2 40.95 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (69620081..69627567)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (69789605..69797223)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10110 Neighboring gene peptidyl-prolyl isomerase G (cyclophilin G) Neighboring gene STARR-positive B cell enhancer mm9_chr2:69582878-69583179 Neighboring gene 60S ribosomal protein L13-like Neighboring gene cilia and flagella associated protein 210 Neighboring gene STARR-seq mESC enhancer starr_04744 Neighboring gene STARR-positive B cell enhancer ABC_E4461 Neighboring gene predicted gene 13624 Neighboring gene predicted gene, 39841

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Probing the substrate specificities of human PHOSPHO1 and PHOSPHO2. Roberts SJ, et al. Biochim Biophys Acta, 2005 Aug 31. PMID 16054448
  2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables pyridoxal phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
pyridoxal phosphate phosphatase PHOSPHO2
NP_082797.1
XP_006500320.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028521.2 → NP_082797.1  pyridoxal phosphate phosphatase PHOSPHO2

    See identical proteins and their annotated locations for NP_082797.1

    Status: PROVISIONAL

    Source sequence(s)
    AK006724
    Consensus CDS
    CCDS16099.1
    UniProtKB/Swiss-Prot
    A2AR04, Q3V1M5, Q9D9M5
    Related
    ENSMUSP00000028494.3, ENSMUST00000028494.9
    Conserved Domains (1) summary
    pfam06888
    Location:3 → 239
    Put_Phosphatase; Putative Phosphatase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    69620081..69627567
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500257.3 → XP_006500320.1  pyridoxal phosphate phosphatase PHOSPHO2 isoform X1

    See identical proteins and their annotated locations for XP_006500320.1

    UniProtKB/Swiss-Prot
    A2AR04, Q3V1M5, Q9D9M5
    Related
    ENSMUSP00000136471.2, ENSMUST00000180290.2
    Conserved Domains (1) summary
    pfam06888
    Location:3 → 239
    Put_Phosphatase; Putative Phosphatase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D9M5.1 GenPept UniProtKB/Swiss-Prot:Q9D9M5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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