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Atxn7l2 ataxin 7-like 2 [ Mus musculus (house mouse) ]

Gene ID: 72522, updated on 5-Mar-2024

Summary

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Official Symbol
Atxn7l2provided by MGI
Official Full Name
ataxin 7-like 2provided by MGI
Primary source
MGI:MGI:1919772
See related
Ensembl:ENSMUSG00000048997 AllianceGenome:MGI:1919772
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610528J18Rik
Summary
Orthologous to human ATXN7L2 (ataxin 7 like 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E14 (RPKM 15.1), whole brain E14.5 (RPKM 13.9) and 27 other tissues See more
Orthologs
human all
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Genomic context

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See Atxn7l2 in Genome Data Viewer
Location:
3 F2.3; 3 46.87 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (108109538..108117843, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (108202222..108210577, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40122 Neighboring gene adhesion molecule with Ig like domain 1 Neighboring gene cytochrome b-561 domain containing 1 Neighboring gene synaptophysin like 2 Neighboring gene SIVA1, apoptosis-inducing factor pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Apr 30. PMID 15449545
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
ataxin-7-like protein 2
Names
mFLJ00381 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001289545.2 → NP_001276474.1  ataxin-7-like protein 2 isoform 1

    See identical proteins and their annotated locations for NP_001276474.1

    Status: VALIDATED

    Source sequence(s)
    AL671854
    UniProtKB/TrEMBL
    Q5HZJ2
    Conserved Domains (1) summary
    pfam08313
    Location:258 → 321
    SCA7; SCA7, zinc-binding domain

  2. NM_175183.6 → NP_780392.1  ataxin-7-like protein 2 isoform 2

    See identical proteins and their annotated locations for NP_780392.1

    Status: VALIDATED

    Source sequence(s)
    AL671854
    Consensus CDS
    CCDS17754.1
    UniProtKB/TrEMBL
    B7ZMR6, Q5HZJ2, Q8C8K6
    Related
    ENSMUSP00000099693.3, ENSMUST00000102633.9
    Conserved Domains (1) summary
    pfam08313
    Location:200 → 263
    SCA7; SCA7, zinc-binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    108109538..108117843 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006502137.4 → XP_006502200.1  ataxin-7-like protein 2 isoform X2

    UniProtKB/TrEMBL
    B7ZCC3
    Related
    ENSMUSP00000112976.2, ENSMUST00000117409.8
    Conserved Domains (1) summary
    pfam08313
    Location:226 → 289
    SCA7; zinc-binding domain

  2. XM_006502136.2 → XP_006502199.1  ataxin-7-like protein 2 isoform X1

    UniProtKB/TrEMBL
    Q5HZJ2
    Conserved Domains (2) summary
    COG5602
    Location:151 → 354
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]
    pfam08313
    Location:226 → 289
    SCA7; zinc-binding domain
Nucleotide Protein Strain
Heading Accession and Version

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