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Zfp654 zinc finger protein 654 [ Mus musculus (house mouse) ]

Gene ID: 72020, updated on 30-Apr-2024

Summary

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Official Symbol
Zfp654provided by MGI
Official Full Name
zinc finger protein 654provided by MGI
Primary source
MGI:MGI:1919270
See related
Ensembl:ENSMUSG00000047141 AllianceGenome:MGI:1919270
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
433036; Gm5488; Znf654; 1600021C16Rik; 1810008K20Rik
Summary
Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZNF654 (zinc finger protein 654). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 17.2), bladder adult (RPKM 2.8) and 12 other tissues See more
Orthologs
human all
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Genomic context

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Location:
16 C1.3; 16 37.1 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (64600710..64672300, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (64780347..64851937, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene casein kinase 2, alpha prime interacting protein Neighboring gene STARR-seq mESC enhancer starr_41145 Neighboring gene STARR-seq mESC enhancer starr_41146 Neighboring gene RIKEN cDNA 4930453N24 gene Neighboring gene STARR-seq mESC enhancer starr_41148 Neighboring gene STARR-positive B cell enhancer mm9_chr16:64851511-64851812 Neighboring gene STARR-seq mESC enhancer starr_41150 Neighboring gene CGG triplet repeat binding protein 1 Neighboring gene predicted gene, 33971

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 654

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347245.1 → NP_001334174.1  zinc finger protein 654

    Status: VALIDATED

    Source sequence(s)
    BC068018, CT030641
    Consensus CDS
    CCDS84250.1
    UniProtKB/Swiss-Prot
    A0A140LI34, Q8K390, Q9DAU9
    Related
    ENSMUSP00000146656.2, ENSMUST00000207826.2
    Conserved Domains (3) summary
    sd00017
    Location:781 → 801
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:541 → 560
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd20908
    Location:538 → 607
    SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    64600710..64672300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011246018.3 → XP_011244320.1  zinc finger protein 654 isoform X1

    Conserved Domains (2) summary
    sd00017
    Location:569 → 589
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:329 → 348
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. XR_003951833.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_028059.2: Suppressed sequence

    Description
    NM_028059.2: This RefSeq was removed because it is though to represent a partial transcript.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DAU9.3 GenPept UniProtKB/Swiss-Prot:Q9DAU9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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