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ARHGAP22 Rho GTPase activating protein 22 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 710956, updated on 5-Mar-2024

Summary

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Official Symbol
ARHGAP22provided by VGNC
Official Full Name
Rho GTPase activating protein 22provided by VGNC
Primary source
VGNC:VGNC:69931
See related
Ensembl:ENSMMUG00000004063
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
13
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (48713115..48923163)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (42550879..42760814, complement)

Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene WDFY family member 4 Neighboring gene uncharacterized LOC107000120 Neighboring gene 60S ribosomal protein L13a pseudogene Neighboring gene uncharacterized LOC114669946 Neighboring gene mitogen-activated protein kinase 8 Neighboring gene uncharacterized LOC107000119

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 22

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041762.1 Reference Mmul_10 Primary Assembly

    Range
    48713115..48923163
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028826344.1 → XP_028682177.1  rho GTPase-activating protein 22 isoform X7

    Conserved Domains (2) summary
    cl02570
    Location:114 → 210
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl17171
    Location:42 → 127
    PH-like; Pleckstrin homology-like domain

  2. XM_015146986.2 → XP_015002472.1  rho GTPase-activating protein 22 isoform X1

    UniProtKB/TrEMBL
    A0A1D5QK46, F7E581
    Related
    ENSMMUP00000048419.2, ENSMMUT00000073726.2
    Conserved Domains (4) summary
    cd04390
    Location:173 → 371
    RhoGAP_ARHGAP22_24_25; RhoGAP_ARHGAP22_24_25: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been ...
    cd13378
    Location:42 → 157
    PH_RhoGAP2; Rho GTPase activating protein 2 Pleckstrin homology (PH) domain
    pfam00169
    Location:44 → 150
    PH; PH domain
    cl03075
    Location:572 → 684
    GrpE; nucleotide exchange factor GrpE

  3. XM_001108566.4 → XP_001108566.1  rho GTPase-activating protein 22 isoform X3

    UniProtKB/TrEMBL
    F7E581
    Related
    ENSMMUP00000035932.3, ENSMMUT00000042922.3
    Conserved Domains (4) summary
    cd04390
    Location:157 → 355
    RhoGAP_ARHGAP22_24_25; RhoGAP_ARHGAP22_24_25: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been ...
    cd13378
    Location:42 → 157
    PH_RhoGAP2; Rho GTPase activating protein 2 Pleckstrin homology (PH) domain
    pfam00169
    Location:44 → 150
    PH; PH domain
    cl03075
    Location:556 → 668
    GrpE; nucleotide exchange factor GrpE

  4. XM_002805637.3 → XP_002805683.1  rho GTPase-activating protein 22 isoform X2

    UniProtKB/TrEMBL
    F6ZKA6, F7E581
    Related
    ENSMMUP00000005432.4, ENSMMUT00000005769.4
    Conserved Domains (4) summary
    cd04390
    Location:167 → 365
    RhoGAP_ARHGAP22_24_25; RhoGAP_ARHGAP22_24_25: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been ...
    cd13378
    Location:36 → 151
    PH_RhoGAP2; Rho GTPase activating protein 2 Pleckstrin homology (PH) domain
    pfam00169
    Location:38 → 144
    PH; PH domain
    cl03075
    Location:566 → 678
    GrpE; nucleotide exchange factor GrpE

  5. XM_028826341.1 → XP_028682174.1  rho GTPase-activating protein 22 isoform X5

    UniProtKB/TrEMBL
    F7E581
    Conserved Domains (3) summary
    COG1196
    Location:546 → 634
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd04390
    Location:108 → 306
    RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
    cl17171
    Location:36 → 121
    PH-like; Pleckstrin homology-like domain

  6. XM_001108619.4 → XP_001108619.1  rho GTPase-activating protein 22 isoform X4

    UniProtKB/TrEMBL
    F7E581
    Conserved Domains (4) summary
    cd04390
    Location:151 → 349
    RhoGAP_ARHGAP22_24_25; RhoGAP_ARHGAP22_24_25: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been ...
    cd13378
    Location:36 → 151
    PH_RhoGAP2; Rho GTPase activating protein 2 Pleckstrin homology (PH) domain
    pfam00169
    Location:38 → 144
    PH; PH domain
    cl03075
    Location:550 → 662
    GrpE; nucleotide exchange factor GrpE

  7. XM_028826342.1 → XP_028682175.1  rho GTPase-activating protein 22 isoform X6

    UniProtKB/TrEMBL
    F7E569
    Related
    ENSMMUP00000035933.2, ENSMMUT00000042923.3
    Conserved Domains (3) summary
    COG1196
    Location:515 → 603
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd04390
    Location:77 → 275
    RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
    cl17171
    Location:18 → 61
    PH-like; Pleckstrin homology-like domain

RNA

  1. XR_003719310.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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