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Dhrs13 dehydrogenase/reductase 13 [ Mus musculus (house mouse) ]

Gene ID: 70451, updated on 5-Mar-2024

Summary

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Official Symbol
Dhrs13provided by MGI
Official Full Name
dehydrogenase/reductase 13provided by MGI
Primary source
MGI:MGI:1917701
See related
Ensembl:ENSMUSG00000020834 AllianceGenome:MGI:1917701
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610209N15Rik
Summary
Predicted to enable NADP-retinol dehydrogenase activity. Predicted to be involved in retinal metabolic process. Predicted to be located in extracellular region. Predicted to be active in mitochondrial inner membrane. Orthologous to human DHRS13 (dehydrogenase/reductase 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 9.9), adrenal adult (RPKM 9.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Dhrs13 in Genome Data Viewer
Location:
11 B5; 11 46.74 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (77923139..77928690)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (78032313..78037864)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_30082 Neighboring gene predicted gene, 53689 Neighboring gene PHD finger protein 12 Neighboring gene predicted gene, 51908 Neighboring gene STARR-positive B cell enhancer ABC_E10693 Neighboring gene dehydrogenase/reductase 13, opposite strand Neighboring gene flotillin 2 Neighboring gene predicted gene, 57805 Neighboring gene microRNA 144

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development. Silvestri C, et al. Dev Cell, 2008 Mar. PMID 18331719
  2. New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. Das R, et al. J Cell Sci, 2019 Jun 17. PMID 31138677, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
  5. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC141618

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
dehydrogenase/reductase SDR family member 13
Names
androgen-regulated short-chain dehydrogenase/reductase 1; prostate short-chain dehydrogenase reductase 1; likely ortholog of mouse cell line MC/9.IL4 derived transcript 1; CGI-82 protein; HCV core-binding protein
dehydrogenase/reductase (SDR family) member 13
short chain dehydrogenase/reductase family 7C member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183286.2 → NP_899109.2  dehydrogenase/reductase SDR family member 13 precursor

    See identical proteins and their annotated locations for NP_899109.2

    Status: VALIDATED

    Source sequence(s)
    AK046465, BB637905
    Consensus CDS
    CCDS36236.1
    UniProtKB/Swiss-Prot
    Q14BH2, Q5SS80, Q8BMX8
    UniProtKB/TrEMBL
    B0QZT2
    Related
    ENSMUSP00000021187.6, ENSMUST00000021187.12
    Conserved Domains (2) summary
    cd05327
    Location:36 → 304
    retinol-DH_like_SDR_c_like; retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs
    PRK06197
    Location:31 → 312
    PRK06197; short chain dehydrogenase; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    77923139..77928690
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5SS80.1 GenPept UniProtKB/Swiss-Prot:Q5SS80

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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