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upk1a uroplakin 1a [ Danio rerio (zebrafish) ]

Gene ID: 678515, updated on 11-Apr-2024

Summary

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Official Symbol
upk1aprovided by ZNC
Official Full Name
uroplakin 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060421-2603
See related
Ensembl:ENSDARG00000021866 AllianceGenome:ZFIN:ZDB-GENE-060421-2603
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb14a02; fk84c04; wu:fb14a02; wu:fk84c04; zgc:136832
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Orthologous to human UPK1A (uroplakin 1A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (44768329..44780744)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (44801612..44814028)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene protein FAM83A Neighboring gene zmp:0000000951 Neighboring gene Rho GTPase activating protein 33 Neighboring gene RNA binding motif protein 42

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Origin of the tetraspanin uroplakins and their co-evolution with associated proteins: implications for uroplakin structure and function. Garcia-España A, et al. Mol Phylogenet Evol, 2006 Nov. PMID 16814572
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC136832

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uroplakin-1a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040242.1 → NP_001035332.1  uroplakin-1a

    See identical proteins and their annotated locations for NP_001035332.1

    Status: PROVISIONAL

    Source sequence(s)
    BC115285
    UniProtKB/TrEMBL
    A0A8M2B4S7, Q1RLU3
    Related
    ENSDARP00000037144.7, ENSDART00000036302.8
    Conserved Domains (2) summary
    cd03156
    Location:103 → 221
    uroplakin_I_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    pfam00335
    Location:30 → 246
    Tetraspannin; Tetraspanin family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    44768329..44780744
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005158400.4 → XP_005158457.1  uroplakin-1a isoform X1

    See identical proteins and their annotated locations for XP_005158457.1

    UniProtKB/TrEMBL
    A0A8M2B4S7, Q1RLU3
    Conserved Domains (2) summary
    cd03156
    Location:103 → 221
    uroplakin_I_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    pfam00335
    Location:30 → 246
    Tetraspannin; Tetraspanin family
Nucleotide Protein Strain
Heading Accession and Version

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