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Saxo4 stabilizer of axonemal microtubules 4 [ Mus musculus (house mouse) ]

Gene ID: 67752, updated on 30-Apr-2024

Summary

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Official Symbol
Saxo4provided by MGI
Official Full Name
stabilizer of axonemal microtubules 4provided by MGI
Primary source
MGI:MGI:1915002
See related
Ensembl:ENSMUSG00000035179 AllianceGenome:MGI:1915002
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IIIG9; IIIG9L; IIIG9S; Ppp1r32; 4930579J09Rik
Summary
Predicted to enable phosphatase binding activity. Predicted to be located in ciliary basal body. Is expressed in lung; male reproductive gland or organ; olfactory lobe; and oviduct. Orthologous to human PPP1R32 (protein phosphatase 1 regulatory subunit 32). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 129.8) See more
Orthologs
human all
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Genomic context

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See Saxo4 in Genome Data Viewer
Location:
19 A; 19 6.6 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (10451599..10463826, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (10474235..10491451, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene synaptotagmin VII Neighboring gene leucine rich repeat containing 10B Neighboring gene succinate dehydrogenase complex assembly factor 2 Neighboring gene cleavage and polyadenylation specific factor 7 Neighboring gene transmembrane protein 216

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A novel mRNA expressed along brain ventricles. Danielson PE, et al. Brain Res Gene Expr Patterns, 2002 Jan. PMID 15018803
  2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

Clone Names

  • MGC144717

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables phosphatase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatase binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in axonemal A tubule inner sheath IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in axonemal A tubule inner sheath TAS
Traceable Author Statement
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
  
located_in cilium ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
stabilizer of axonemal microtubules 4
Names
protein phosphatase 1, regulatory subunit 32

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368184.1 → NP_001355113.1  stabilizer of axonemal microtubules 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AK005821, AK016325, AY032666, BX630729
    Consensus CDS
    CCDS29577.1
    UniProtKB/Swiss-Prot
    Q148A4, Q91XJ2
    UniProtKB/TrEMBL
    A0A0R4J0F3
    Related
    ENSMUSP00000158578.2, ENSMUST00000237522.2
    Conserved Domains (1) summary
    pfam15691
    Location:2 → 418
    PPP1R32; Protein phosphatase 1 regulatory subunit 32

  2. NM_133689.2 → NP_598450.1  stabilizer of axonemal microtubules 4

    See identical proteins and their annotated locations for NP_598450.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AK005821, AY032666, BX630729
    Consensus CDS
    CCDS29577.1
    UniProtKB/Swiss-Prot
    Q148A4, Q91XJ2
    UniProtKB/TrEMBL
    A0A0R4J0F3
    Related
    ENSMUSP00000035684.4, ENSMUST00000038842.5
    Conserved Domains (1) summary
    pfam15691
    Location:2 → 418
    PPP1R32; Protein phosphatase 1 regulatory subunit 32

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    10451599..10463826 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017318282.1 → XP_017173771.1  stabilizer of axonemal microtubules 4 isoform X1

    UniProtKB/Swiss-Prot
    Q148A4, Q91XJ2
    UniProtKB/TrEMBL
    A0A0R4J0F3
    Conserved Domains (1) summary
    pfam15691
    Location:2 → 418
    PPP1R32; Protein phosphatase 1 regulatory subunit 32

  2. XM_036161672.1 → XP_036017565.1  stabilizer of axonemal microtubules 4 isoform X2

    UniProtKB/TrEMBL
    A0A494B8Y3
    Related
    ENSMUSP00000157403.2, ENSMUST00000235392.2
    Conserved Domains (1) summary
    pfam15691
    Location:1 → 244
    PPP1R32; Protein phosphatase 1 regulatory subunit 32

  3. XM_017318281.1 → XP_017173770.1  stabilizer of axonemal microtubules 4 isoform X1

    UniProtKB/Swiss-Prot
    Q148A4, Q91XJ2
    UniProtKB/TrEMBL
    A0A0R4J0F3
    Conserved Domains (1) summary
    pfam15691
    Location:2 → 418
    PPP1R32; Protein phosphatase 1 regulatory subunit 32

  4. XM_006527302.5 → XP_006527365.1  stabilizer of axonemal microtubules 4 isoform X1

    See identical proteins and their annotated locations for XP_006527365.1

    UniProtKB/Swiss-Prot
    Q148A4, Q91XJ2
    UniProtKB/TrEMBL
    A0A0R4J0F3
    Conserved Domains (1) summary
    pfam15691
    Location:2 → 418
    PPP1R32; Protein phosphatase 1 regulatory subunit 32
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q148A4.1 GenPept UniProtKB/Swiss-Prot:Q148A4

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