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Mtcl3 MTCL family member 3 [ Mus musculus (house mouse) ]

Gene ID: 67412, updated on 5-Mar-2024

Summary

Official Symbol
Mtcl3provided by MGI
Official Full Name
MTCL family member 3provided by MGI
Primary source
MGI:MGI:1914662
See related
Ensembl:ENSMUSG00000038916 AllianceGenome:MGI:1914662
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Soga3; 6330407J23Rik
Summary
Predicted to be involved in regulation of autophagy. Predicted to be located in extracellular space and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; heart; integumental system; nervous system; and sensory organ. Orthologous to human SOGA3 (SOGA family member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in whole brain E14.5 (RPKM 19.0), CNS E18 (RPKM 16.3) and 5 other tissues See more
Orthologs
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Genomic context

Location:
10 A4; 10 16.52 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (29019992..29075626)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (29143996..29199630)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene UPF0762 protein C6orf58 homolog Neighboring gene phosphatidylethanolamine-binding protein pseudogene Neighboring gene STARR-seq mESC enhancer starr_26173 Neighboring gene STARR-seq mESC enhancer starr_26174 Neighboring gene RIKEN cDNA 9330159F19 gene Neighboring gene STARR-seq mESC enhancer starr_26176 Neighboring gene predicted gene, 46218 Neighboring gene STARR-seq mESC enhancer starr_26177 Neighboring gene enoyl Coenzyme A hydratase domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E6827 Neighboring gene ring finger protein 146 Neighboring gene predicted gene, 25596

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in regulation of autophagy IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
microtubule cross-linking factor 3
Names
SOGA family member 3
protein SOGA3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026138.2NP_080414.2  microtubule cross-linking factor 3 precursor

    See identical proteins and their annotated locations for NP_080414.2

    Status: VALIDATED

    Source sequence(s)
    AC153912, AK018139, AK030682, CD355864
    Consensus CDS
    CCDS35875.1
    UniProtKB/Swiss-Prot
    Q6NZL0, Q8BLM2, Q9CSN3, Q9CU45
    Related
    ENSMUSP00000090293.3, ENSMUST00000092629.4
    Conserved Domains (2) summary
    pfam00261
    Location:357569
    Tropomyosin; Tropomyosin
    pfam11365
    Location:519613
    DUF3166; Protein of unknown function (DUF3166)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    29019992..29075626
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)