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Ankrd61 ankyrin repeat domain 61 [ Mus musculus (house mouse) ]

Gene ID: 66729, updated on 5-Mar-2024

Summary

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Official Symbol
Ankrd61provided by MGI
Official Full Name
ankyrin repeat domain 61provided by MGI
Primary source
MGI:MGI:1913979
See related
Ensembl:ENSMUSG00000029607 AllianceGenome:MGI:1913979
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4921520G13Rik
Summary
Predicted to enable DNA binding activity. Predicted to be located in nucleoplasm. Orthologous to human ANKRD61 (ankyrin repeat domain 61). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 65.4) and liver E14 (RPKM 0.8) See more
Orthologs
human all
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Genomic context

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See Ankrd61 in Genome Data Viewer
Location:
5 G2; 5 82.79 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (143827455..143831885, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (143890637..143895067, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 42 Neighboring gene predicted gene, 38737 Neighboring gene RIKEN cDNA D130017N08 gene Neighboring gene STARR-positive B cell enhancer ABC_E10364 Neighboring gene STARR-positive B cell enhancer ABC_E2182 Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 1 Neighboring gene STARR-positive B cell enhancer ABC_E858 Neighboring gene aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 Neighboring gene PMS1 homolog2, mismatch repair system component Neighboring gene CCZ1 vacuolar protein trafficking and biogenesis associated Neighboring gene predicted gene, 24311

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ankyrin repeat domain-containing protein 61

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310772.1 → NP_001297701.1  ankyrin repeat domain-containing protein 61 isoform 2

    See identical proteins and their annotated locations for NP_001297701.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 5' terminal exon and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) has a shorter, distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AK014929, BC052346
    Consensus CDS
    CCDS80460.1
    UniProtKB/TrEMBL
    D3YXD2
    Related
    ENSMUSP00000078571.6, ENSMUST00000079624.12
    Conserved Domains (4) summary
    cd00204
    Location:122 → 255
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:129 → 232
    Ank_2; Ankyrin repeats (3 copies)
    pfam13857
    Location:220 → 274
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:126 → 155
    ANK; ANK repeat [structural motif]

  2. NM_025732.4 → NP_080008.1  ankyrin repeat domain-containing protein 61 isoform 1

    See identical proteins and their annotated locations for NP_080008.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK014929, BC052346
    Consensus CDS
    CCDS39373.1
    UniProtKB/Swiss-Prot
    Q80W77, Q9CQM6
    UniProtKB/TrEMBL
    D3YXD2
    Related
    ENSMUSP00000106345.3, ENSMUST00000110717.9
    Conserved Domains (4) summary
    cd00204
    Location:164 → 297
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:171 → 274
    Ank_2; Ankyrin repeats (3 copies)
    pfam13857
    Location:262 → 316
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:168 → 197
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    143827455..143831885 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006504859.5 → XP_006504922.1  ankyrin repeat domain-containing protein 61 isoform X1

    UniProtKB/TrEMBL
    D3YXD2
    Conserved Domains (3) summary
    COG0666
    Location:148 → 275
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:54 → 83
    ANK; ANK repeat [structural motif]
    cl39094
    Location:36 → 210
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CQM6.1 GenPept UniProtKB/Swiss-Prot:Q9CQM6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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