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Tceal8 transcription elongation factor A (SII)-like 8 [ Mus musculus (house mouse) ]

Gene ID: 66684, updated on 5-Mar-2024

Summary

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Official Symbol
Tceal8provided by MGI
Official Full Name
transcription elongation factor A (SII)-like 8provided by MGI
Primary source
MGI:MGI:1913934
See related
Ensembl:ENSMUSG00000051579 AllianceGenome:MGI:1913934
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3930402F23Rik
Summary
Predicted to enable WW domain binding activity. Predicted to be active in nucleus. Is expressed in genitourinary system and limb. Orthologous to human TCEAL8 (transcription elongation factor A like 8). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in placenta adult (RPKM 40.4), liver E14 (RPKM 36.2) and 14 other tissues See more
Orthologs
human all
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Genomic context

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See Tceal8 in Genome Data Viewer
Location:
X F1; X 57.4 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (135069733..135073000, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (136168984..136172251, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene nuclear RNA export factor 3 Neighboring gene RIKEN cDNA 5730412P04 gene Neighboring gene brain expressed X-linked 4 Neighboring gene microRNA 6383 Neighboring gene predicted gene, 41901 Neighboring gene nuclear encoded tRNA lysine 19 (anticodon CTT)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes. Judd J, et al. Sci Rep, 2019 Dec 11. PMID 31827131, Free PMC Article
  2. Interaction between nucleosome assembly protein 1-like family members. Attia M, et al. J Mol Biol, 2011 Apr 15. PMID 21333655
  3. Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions. Navas-Pérez E, et al. Genome Biol, 2020 Oct 26. PMID 33100228, Free PMC Article
  4. A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice. Zhou J, et al. Biol Reprod, 2013 Jun. PMID 23677977, Free PMC Article
  5. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes.
    Title: Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transcription elongation factor A protein-like 8
Names
TCEA-like protein 8
transcription elongation factor S-II protein-like 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168578.1 → NP_001162050.1  transcription elongation factor A protein-like 8

    See identical proteins and their annotated locations for NP_001162050.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL772180
    Consensus CDS
    CCDS30415.1
    UniProtKB/Swiss-Prot
    A2AJR7, Q9CYP9, Q9CZY2
    Related
    ENSMUSP00000129591.2, ENSMUST00000163584.8
    Conserved Domains (1) summary
    pfam04538
    Location:1 → 113
    BEX; Brain expressed X-linked like family

  2. NM_025703.3 → NP_079979.2  transcription elongation factor A protein-like 8

    See identical proteins and their annotated locations for NP_079979.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AA867696, AK076203, AK083347
    Consensus CDS
    CCDS30415.1
    UniProtKB/Swiss-Prot
    A2AJR7, Q9CYP9, Q9CZY2
    Related
    ENSMUSP00000056189.4, ENSMUST00000060101.10
    Conserved Domains (1) summary
    pfam04538
    Location:1 → 113
    BEX; Brain expressed X-linked like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    135069733..135073000 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CZY2.1 GenPept UniProtKB/Swiss-Prot:Q9CZY2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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