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Mfsd14b major facilitator superfamily domain containing 14B [ Mus musculus (house mouse) ]

Gene ID: 66631, updated on 5-Mar-2024

Summary

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Official Symbol
Mfsd14bprovided by MGI
Official Full Name
major facilitator superfamily domain containing 14Bprovided by MGI
Primary source
MGI:MGI:1913881
See related
Ensembl:ENSMUSG00000038212 AllianceGenome:MGI:1913881
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hiatl1; 5730414C17Rik
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human MFSD14B (major facilitator superfamily domain containing 14B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 14.5), placenta adult (RPKM 12.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
13 B3; 13 34.21 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (65212843..65260813, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (65065030..65112999, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 31 subfamily D, member 1C Neighboring gene serine protease 47 Neighboring gene predicted gene 3785 Neighboring gene olfactory receptor family 14 subfamily P member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
  2. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Murn J, et al. Genes Dev, 2015 Mar 1. PMID 25737280, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
hippocampus abundant transcript-like protein 1
Names
hippocampus abundant transcript-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083901.2 → NP_001077370.1  hippocampus abundant transcript-like protein 1

    See identical proteins and their annotated locations for NP_001077370.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    AC154713
    Consensus CDS
    CCDS26603.2
    UniProtKB/Swiss-Prot
    G3UVV2, Q8CIA9, Q8VCW0
    Related
    ENSMUSP00000062566.9, ENSMUST00000054730.10
    Conserved Domains (1) summary
    cd17387
    Location:47 → 452
    MFS_MFSD14; Major facilitator superfamily domain-containing 14A and 14B

  2. NM_133680.4 → NP_598441.3  hippocampus abundant transcript-like protein 1

    See identical proteins and their annotated locations for NP_598441.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AC154713
    Consensus CDS
    CCDS26603.2
    UniProtKB/Swiss-Prot
    G3UVV2, Q8CIA9, Q8VCW0
    Related
    ENSMUSP00000118180.2, ENSMUST00000155487.8
    Conserved Domains (1) summary
    cd17387
    Location:47 → 452
    MFS_MFSD14; Major facilitator superfamily domain-containing 14A and 14B

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    65212843..65260813 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011244550.4 → XP_011242852.1  hippocampus abundant transcript-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011242852.1

    UniProtKB/Swiss-Prot
    G3UVV2, Q8CIA9, Q8VCW0
    Conserved Domains (1) summary
    cd17387
    Location:47 → 452
    MFS_MFSD14; Major facilitator superfamily domain-containing 14A and 14B
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CIA9.3 GenPept UniProtKB/Swiss-Prot:Q8CIA9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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