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Keg1 kidney expressed gene 1 [ Mus musculus (house mouse) ]

Gene ID: 64697, updated on 8-Feb-2024

Summary

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Official Symbol
Keg1provided by MGI
Official Full Name
kidney expressed gene 1provided by MGI
Primary source
MGI:MGI:1928492
See related
Ensembl:ENSMUSG00000024694 AllianceGenome:MGI:1928492
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GS4059; 0610008P16Rik
Summary
Predicted to enable glycine N-acyltransferase activity and glycine N-benzoyltransferase activity. Predicted to be involved in benzoyl-CoA metabolic process and glycine metabolic process. Located in mitochondrion. Is expressed in several structures, including genitourinary system and liver. Orthologous to human GLYAT (glycine-N-acyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward kidney adult (RPKM 563.1) See more
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Genomic context

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See Keg1 in Genome Data Viewer
Location:
19 A; 19 8.73 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (12673154..12697266)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (12695790..12719902)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily B member 94 Neighboring gene olfactory receptor family 5 subfamily B member 95 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_45598 Neighboring gene predicted readthrough transcript (NMD candidate), 44505 Neighboring gene ciliary neurotrophic factor Neighboring gene zinc finger protein 91 Neighboring gene STARR-positive B cell enhancer ABC_E11024 Neighboring gene STARR-positive B cell enhancer ABC_E4268 Neighboring gene leupaxin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. HP33: hepatocellular carcinoma-enriched 33-kDa protein with similarity to mitochondrial N-acyltransferase but localized in a microtubule-dependent manner at the centrosome. Nakadai T, et al. J Cell Sci, 1999 May. PMID 10194414
  2. Structure of rat gamma-tubulin and its binding to HP33. Nakadai T, et al. DNA Res, 1999 Jun 30. PMID 10470852
  3. Isolation of genes identified in mouse renal proximal tubule by comparing different gene expression profiles. Takenaka M, et al. Kidney Int, 1998 Mar. PMID 9507200
  4. Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Kim SC, et al. Mol Cell, 2006 Aug. PMID 16916647
  5. Deterministic and stochastic allele specific gene expression in single mouse blastomeres. Tang F, et al. PLoS One, 2011. PMID 21731673, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycine N-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
colocalizes_with centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
glycine N-acyltransferase-like protein Keg1
Names
Acyl-CoA:glycine N-acyltransferase protein Keg1
kidney-expressed gene 1 protein
NP_083826.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029550.4 → NP_083826.1  glycine N-acyltransferase-like protein Keg1

    See identical proteins and their annotated locations for NP_083826.1

    Status: VALIDATED

    Source sequence(s)
    AC150901, AI099383, AK165515
    Consensus CDS
    CCDS29636.1
    UniProtKB/Swiss-Prot
    Q9DCY0
    Related
    ENSMUSP00000025598.4, ENSMUST00000025598.10
    Conserved Domains (2) summary
    pfam08444
    Location:206 → 294
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:10 → 205
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    12673154..12697266
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DCY0.1 GenPept UniProtKB/Swiss-Prot:Q9DCY0

Gene LinkOut

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