zgc:122979 zgc:122979 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zgc:122979provided by ZNC
Official Full Name: zgc:122979provided by ZNC
Primary source: ZFIN:ZDB-GENE-051127-45
See related: Ensembl:ENSDARG00000004187 AllianceGenome:ZFIN:ZDB-GENE-051127-45
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:152710
Summary: Predicted to enable chaperone binding activity and unfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to act upstream of or within protein folding. Predicted to be active in cytosol. Orthologous to human DNAJB5 (DnaJ heat shock protein family (Hsp40) member B5). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 21

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (5169154..5174056)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (5004589..5009491)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein-folding chaperone binding	IBA Inferred from Biological aspect of Ancestor more info
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables unfolded protein binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in chaperone cofactor-dependent protein refolding	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein folding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein LOC641576

Names: DnaJ (Hsp40) homolog, subfamily B, member 5-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001037574.2 → NP_001032663.2 uncharacterized protein LOC641576

Status: VALIDATED

Source sequence(s)

CR382296, EE309334, EH446867, EH456176

UniProtKB/TrEMBL

A0A8M1N830, F1R1Q6

Related

ENSDARP00000093335.3, ENSDART00000102559.5

Conserved Domains (3) summary

cd10747
Location:185 → 345

DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40

COG0484
Location:50 → 355

DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]

pfam00226
Location:51 → 112

DnaJ; DnaJ domain