ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif 19 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ADAMTS19provided by VGNC
Official Full Name: ADAM metallopeptidase with thrombospondin type 1 motif 19provided by VGNC
Primary source: VGNC:VGNC:37597
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 11

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	11	NC_051815.1 (19039211..19255681)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	11	NC_006593.4 (17072306..17300168)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	11	NC_049232.1 (18199198..18428137)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	11	NC_049271.1 (17747255..17980124)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	11	NC_049752.1 (17585712..17814466)

Chromosome 11 - NC_051815.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

NCBI Orthologs

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables metalloendopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in extracellular matrix organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular matrix	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: A disintegrin and metalloproteinase with thrombospondin motifs 19

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051815.1 Reference ROS_Cfam_1.0

Range

19039211..19255681

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038681420.1 → XP_038537348.1 A disintegrin and metalloproteinase with thrombospondin motifs 19 isoform X1

UniProtKB/TrEMBL

A0A8C0KKH6

Conserved Domains (6) summary

smart00209
Location:394 → 443

TSP1; Thrombospondin type 1 repeats

cd04273
Location:82 → 299

ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...

pfam05986
Location:547 → 657

ADAM_spacer1; ADAM-TS Spacer 1

pfam01562
Location:2 → 30

Pep_M12B_propep; Reprolysin family propeptide

pfam17771
Location:316 → 383

ADAM_CR_2; ADAM cysteine-rich domain

pfam19030
Location:848 → 900

TSP1_ADAMTS; Thrombospondin type 1 domain

Alternate UMICH_Zoey_3.1

Genomic

NC_049271.1 Alternate UMICH_Zoey_3.1

Range

17747255..17980124

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038491150.1 → XP_038347078.1 A disintegrin and metalloproteinase with thrombospondin motifs 19 isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049752.1 Alternate UNSW_CanFamBas_1.0

Range

17585712..17814466

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038615549.1 → XP_038471477.1 A disintegrin and metalloproteinase with thrombospondin motifs 19 isoform X3

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049232.1 Alternate UU_Cfam_GSD_1.0

Range

18199198..18428137

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038551654.1 → XP_038407582.1 A disintegrin and metalloproteinase with thrombospondin motifs 19 isoform X4

UniProtKB/TrEMBL

A0A8I3RTV1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

17072306..17300168

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038660531.1 → XP_038516459.1 A disintegrin and metalloproteinase with thrombospondin motifs 19 isoform X5

UniProtKB/TrEMBL

A0A8P0N3X0

Conserved Domains (6) summary

smart00209
Location:709 → 758

TSP1; Thrombospondin type 1 repeats

cd04273
Location:397 → 614

ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...

pfam05986
Location:862 → 972

ADAM_spacer1; ADAM-TS Spacer 1

pfam01562
Location:230 → 345

Pep_M12B_propep; Reprolysin family propeptide

pfam17771
Location:631 → 698

ADAM_CR_2; ADAM cysteine-rich domain

pfam19030
Location:1163 → 1215

TSP1_ADAMTS; Thrombospondin type 1 domain