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ctnnbip1 catenin, beta interacting protein 1 [ Danio rerio (zebrafish) ]

Gene ID: 58117, updated on 27-Mar-2024

Summary

Official Symbol
ctnnbip1provided by ZNC
Official Full Name
catenin, beta interacting protein 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-000906-3
See related
Ensembl:ENSDARG00000038954 AllianceGenome:ZFIN:ZDB-GENE-000906-3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
icat; fa95e12; wu:fa95e12
Summary
Predicted to enable beta-catenin binding activity. Predicted to be involved in negative regulation of Wnt signaling pathway. Predicted to be part of beta-catenin destruction complex. Predicted to be active in cytosol and nucleus. Is expressed in central nervous system and optic tectum. Orthologous to human CTNNBIP1 (catenin beta interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 23
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (29711569..29751730, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (29785028..29825189, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene leucine zipper and CTNNBIP1 domain containing Neighboring gene calsyntenin 1 Neighboring gene phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta Neighboring gene forkhead box L2-like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables beta-catenin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in negative regulation of Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within negative regulation of Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of beta-catenin destruction complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
beta-catenin-interacting protein 1
Names
beta-catenin-interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131594.1NP_571669.1  beta-catenin-interacting protein 1

    See identical proteins and their annotated locations for NP_571669.1

    Status: PROVISIONAL

    Source sequence(s)
    AB046866
    UniProtKB/TrEMBL
    Q789J2, Q9I903
    Related
    ENSDARP00000056864.4, ENSDART00000056865.6
    Conserved Domains (1) summary
    pfam06384
    Location:179
    ICAT; Beta-catenin-interacting protein ICAT

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    29711569..29751730 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)