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AR androgen receptor [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 574293, updated on 5-Mar-2024

Summary

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Official Symbol
ARprovided by VGNC
Official Full Name
androgen receptorprovided by VGNC
Primary source
VGNC:VGNC:103789
See related
Ensembl:ENSMMUG00000011437
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
8
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (64527705..64691786)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (62123719..62287821)

Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene signal transducer CD24-like Neighboring gene protein transport protein Sec61 subunit beta Neighboring gene polycomb complex protein BMI-1 pseudogene Neighboring gene protein argonaute-3-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Partial agonist/antagonist properties of androstenedione and 4-androsten-3beta,17beta-diol. Chen F, et al. J Steroid Biochem Mol Biol, 2004 Aug. PMID 15336702
  2. Androgen receptor messenger ribonucleic acid in brains and pituitaries of male rhesus monkeys: studies on distribution, hormonal control, and relationship to luteinizing hormone secretion. Abdelgadir SE, et al. Biol Reprod, 1999 May. PMID 10208992
  3. Effect of heat stress on expression of junction-associated molecules and upstream factors androgen receptor and Wilms' tumor 1 in monkey sertoli cells. Chen M, et al. Endocrinology, 2008 Oct. PMID 18535113
  4. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Androgen receptor (AR) and Wilms' tumor gene 1 expression dramatically decreased after heat treatment in Sertoli cells
    Title: Effect of heat stress on expression of junction-associated molecules and upstream factors androgen receptor and Wilms' tumor 1 in monkey sertoli cells.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in androgen receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in male gonad development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
androgen receptor
Names
dihydrotestosterone receptor
nuclear receptor subfamily 3 group C member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001032911.1 → NP_001028083.1  androgen receptor

    See identical proteins and their annotated locations for NP_001028083.1

    Status: PROVISIONAL

    Source sequence(s)
    AY526325
    UniProtKB/Swiss-Prot
    O97891, Q6QT55
    UniProtKB/TrEMBL
    G7NRS8
    Related
    ENSMMUP00000015004.4, ENSMMUT00000016011.4
    Conserved Domains (3) summary
    cd07073
    Location:648 → 893
    NR_LBD_AR; Ligand binding domain of the nuclear receptor androgen receptor, ligand activated transcription regulator
    cd07173
    Location:530 → 611
    NR_DBD_AR; DNA-binding domain of androgen receptor (AR) is composed of two C4-type zinc fingers
    pfam02166
    Location:6 → 432
    Androgen_recep; Androgen receptor

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041774.1 Reference Mmul_10 Primary Assembly

    Range
    64527705..64691786
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6QT55.1 GenPept UniProtKB/Swiss-Prot:Q6QT55

Gene LinkOut

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Molecular Biology Databases
Research Materials
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