MCCC1 - methylcrotonyl-CoA carboxylase subunit 1
This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. [provided by RefSeq, Jul 2008]
NCBI Orthologs
How was this calculated?genes for:
Protein alignment
Download data
Species | Gene | Architecture | aa |
---|