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hipk3b homeodomain interacting protein kinase 3b [ Danio rerio (zebrafish) ]

Gene ID: 569156, updated on 27-Mar-2024

Summary

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Official Symbol
hipk3bprovided by ZNC
Official Full Name
homeodomain interacting protein kinase 3bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-82
See related
Ensembl:ENSDARG00000062082 AllianceGenome:ZFIN:ZDB-GENE-030131-82
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fd59e05; zeh1150; hm:zeh1150; wu:fd59e05; si:dkey-261h15.1
Summary
Predicted to enable protein serine/threonine kinase activity and protein tyrosine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation and peptidyl-threonine phosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in PML body and cytoplasm. Orthologous to human HIPK3 (homeodomain interacting protein kinase 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
16
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (27904488..27998232)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (27926221..28017423)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene tetraspanin 18b Neighboring gene IQ motif containing G Neighboring gene KIAA1549-like b Neighboring gene uncharacterized LOC103909143 Neighboring gene spondin 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Dynamic transcriptomic profiles of zebrafish gills in response to zinc supplementation. Zheng D, et al. BMC Genomics, 2010 Oct 11. PMID 20937081, Free PMC Article
  2. Identification, characterization, and mapping of expressed sequence tags from an embryonic zebrafish heart cDNA library. Ton C, et al. Genome Res, 2000 Dec. PMID 11116087, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peptidyl-threonine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in PML body IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
homeodomain-interacting protein kinase 3
NP_001073628.1
XP_005159231.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080159.2 → NP_001073628.1  homeodomain-interacting protein kinase 3

    See identical proteins and their annotated locations for NP_001073628.1

    Status: PROVISIONAL

    Source sequence(s)
    BX908394, BX908791
    UniProtKB/TrEMBL
    A0A8M1NCP8, Q1LUZ7
    Related
    ENSDARP00000150978.1, ENSDART00000191835.1
    Conserved Domains (2) summary
    smart00220
    Location:252 → 580
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14229
    Location:251 → 580
    STKc_HIPK3; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 3

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    27904488..27998232
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005159174.4 → XP_005159231.1  homeodomain-interacting protein kinase 3 isoform X1

    See identical proteins and their annotated locations for XP_005159231.1

    UniProtKB/TrEMBL
    A0A8M1NCP8, Q1LUZ7
    Related
    ENSDARP00000119096.1, ENSDART00000142336.2
    Conserved Domains (2) summary
    smart00220
    Location:252 → 580
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14229
    Location:251 → 580
    STKc_HIPK3; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 3
Nucleotide Protein Strain
Heading Accession and Version

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