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ankfy1 ankyrin repeat and FYVE domain containing 1 [ Danio rerio (zebrafish) ]

Gene ID: 568480, updated on 27-Mar-2024

Summary

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Official Symbol
ankfy1provided by ZNC
Official Full Name
ankyrin repeat and FYVE domain containing 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-041222-1
See related
Ensembl:ENSDARG00000061013 AllianceGenome:ZFIN:ZDB-GENE-041222-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fb69g03
Summary
Predicted to enable metal ion binding activity. Orthologous to human ANKFY1 (ankyrin repeat and FYVE domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See ankfy1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
25
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (30996257..31030843)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (30396129..30430687)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative) Neighboring gene ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast) Neighboring gene cytochrome b5 domain containing 2 Neighboring gene zinc finger, ZZ-type with EF hand domain 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
  2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables small GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in Golgi to lysosome transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
rabankyrin-5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001102672.1 → NP_001096142.1  rabankyrin-5

    Status: PROVISIONAL

    Source sequence(s)
    CR753844
    UniProtKB/TrEMBL
    A0A8M1NEE8, A2CER9
    Related
    ENSDARP00000148407.1, ENSDART00000185783.1
    Conserved Domains (7) summary
    smart00225
    Location:73 → 160
    BTB; Broad-Complex, Tramtrack and Bric a brac
    smart00875
    Location:171 → 239
    BACK; BTB And C-terminal Kelch
    cd00204
    Location:864 → 990
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd15728
    Location:1098 → 1160
    FYVE_ANFY1; FYVE domain found in ankyrin repeat and FYVE domain-containing protein 1 (ANFY1) and similar proteins
    pfam00651
    Location:64 → 160
    BTB; BTB/POZ domain
    pfam12796
    Location:908 → 1001
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:906 → 934
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    30996257..31030843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005171905.4 → XP_005171962.1  rabankyrin-5 isoform X1

    UniProtKB/TrEMBL
    A0A0R4IK06, A0A8M2BJB2
    Related
    ENSDARP00000136220.2, ENSDART00000161765.3
    Conserved Domains (7) summary
    smart00225
    Location:73 → 160
    BTB; Broad-Complex, Tramtrack and Bric a brac
    smart00875
    Location:171 → 239
    BACK; BTB And C-terminal Kelch
    cd00204
    Location:864 → 990
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd15728
    Location:1099 → 1161
    FYVE_ANFY1; FYVE domain found in ankyrin repeat and FYVE domain-containing protein 1 (ANFY1) and similar proteins
    pfam00651
    Location:64 → 160
    BTB; BTB/POZ domain
    pfam12796
    Location:908 → 1001
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:906 → 934
    ANK; ANK repeat [structural motif]

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394583.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    280233..312309
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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