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smg8 SMG8 nonsense mediated mRNA decay factor [ Danio rerio (zebrafish) ]

Gene ID: 567424, updated on 27-Mar-2024

Summary

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Official Symbol
smg8provided by ZNC
Official Full Name
SMG8 nonsense mediated mRNA decay factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-091204-279
See related
Ensembl:ENSDARG00000061378 AllianceGenome:ZFIN:ZDB-GENE-091204-279
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-168p1.3
Summary
Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Orthologous to human SMG8 (SMG8 nonsense mediated mRNA decay factor). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (35238271..35248514, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (35294545..35304654, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene POM121 transmembrane nucleoporin Neighboring gene yippee-like 2a Neighboring gene proline rich 11 Neighboring gene serine/threonine/tyrosine interacting-like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein SMG8
Names
smg-8 homolog, nonsense mediated mRNA decay factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    35238271..35248514 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_690719.9 → XP_695811.2  protein SMG8

    UniProtKB/TrEMBL
    A0A8N7T6K6, E7FBA3
    Related
    ENSDARP00000081911.4, ENSDART00000087477.5
    Conserved Domains (1) summary
    pfam10220
    Location:23 → 905
    DUF2146; Uncharacterized conserved protein (DUF2146)
Nucleotide Protein
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