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pigr polymeric immunoglobulin receptor [ Danio rerio (zebrafish) ]

Gene ID: 566471, updated on 11-Apr-2024

Summary

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Official Symbol
pigrprovided by ZNC
Official Full Name
polymeric immunoglobulin receptorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-327
See related
Ensembl:ENSDARG00000101890 AllianceGenome:ZFIN:ZDB-GENE-060503-327
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-9d9.6
Summary
Predicted to enable transmembrane signaling receptor activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 2
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (51613452..51634620, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (52020691..52041888, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101884314 Neighboring gene polymeric immunoglobulin receptor-like Neighboring gene defender against cell death 1 Neighboring gene abhydrolase domain containing 4, N-acyl phospholipase B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Identification and expression of a new Ly6 gene cluster in zebrafish Danio rerio, with implications of being involved in embryonic immunity. Wang M, et al. Fish Shellfish Immunol, 2016 Jul. PMID 27071517
  2. Application of Biomimetic Cell-Derived Nanoparticles with Mannose Modification as a Novel Vaccine Delivery Platform against Teleost Fish Viral Disease. Zhang C, et al. ACS Biomater Sci Eng, 2020 Dec 14. PMID 33320639
  3. Differential expression and ligand binding indicate alternative functions for zebrafish polymeric immunoglobulin receptor (pIgR) and a family of pIgR-like (PIGRL) proteins. Kortum AN, et al. Immunogenetics, 2014 Apr. PMID 24469064, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A single pigr gene has been identified on chromosome 2 along with a large multigene family consisting of 29 pigr-like (PIGRL) genes.
    Title: Differential expression and ligand binding indicate alternative functions for zebrafish polymeric immunoglobulin receptor (pIgR) and a family of pIgR-like (PIGRL) proteins.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables transmembrane signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
polymeric immunoglobulin receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001302250.1 → NP_001289179.1  polymeric immunoglobulin receptor precursor

    See identical proteins and their annotated locations for NP_001289179.1

    Status: PROVISIONAL

    Source sequence(s)
    KF932325
    Related
    ENSDARP00000141970.1, ENSDART00000165568.2
    Conserved Domains (2) summary
    cd05716
    Location:139 → 231
    Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR)
    smart00410
    Location:26 → 127
    IG_like; Immunoglobulin like

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    51613452..51634620 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005163603.4 → XP_005163660.1  polymeric immunoglobulin receptor isoform X1

    Conserved Domains (2) summary
    cd05716
    Location:139 → 231
    Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR)
    smart00410
    Location:26 → 127
    IG_like; Immunoglobulin like
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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